β-defensin 121 is a protein that belongs to the β-defensin family, we can infer general characteristics based on the known properties of β-defensins. These are small, cysteine-rich cationic peptides that are an integral part of the innate immune defense, mainly due to their antimicrobial activity against a broad spectrum of pathogens, including bacteria, viruses, and fungi. Their mechanism of action typically involves permeabilization of microbial membranes, leading to cell death.The β-defensins are also known for their ability to modulate the immune response by acting as signaling molecules. They can attract various immune cells, such as macrophages and dendritic cells, to the site of infection, thereby enhancing the adaptive immune response. Moreover, they may influence the production of cytokines and chemokines, thus playing a role in inflammatory responses.
These peptides are predominantly expressed in epithelial cells, which form barriers on the skin, as well as in the respiratory, gastrointestinal, and urogenital tracts. This strategic expression allows them to act at the front lines of defense against microbial invasion. Expression of β-defensins can be upregulated in response to microbial challenge or inflammatory signals, providing a dynamic response to infection.Should a "β-defensin 121" exist, it would likely share these structural and functional characteristics, contributing to the host's defense mechanisms by both direct antimicrobial action and immune system modulation.
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Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
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Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
La vitamina D3 puede potenciar la expresión de péptidos antimicrobianos, incluidas las β-defensinas, a través de la vía del receptor de la vitamina D (VDR). | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $63.00 $174.00 | ||
El butirato, un ácido graso de cadena corta producido por la microbiota intestinal, puede aumentar la expresión de defensina en el epitelio intestinal. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
La forma activa de la vitamina D desempeña un papel en la estimulación del sistema inmunitario y puede aumentar la expresión de la β-defensina. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
L'acide rétinoïque, dérivé de la vitamine A, influence les réponses immunitaires et peut renforcer l'expression de la β-défensine. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
El LPS, un componente de la membrana externa de las bacterias Gram negativas, puede inducir la expresión de β-defensina como parte de la respuesta inmunitaria. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
El zinc es crucial para la función inmunitaria y se ha demostrado que influye en la expresión de diversas defensinas. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Le resvératrol, un polyphénol, peut moduler les réponses immunitaires et potentiellement augmenter l'expression de la β-défensine. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
La curcumina tiene propiedades antiinflamatorias y podría influir en la expresión de péptidos antimicrobianos, incluidas las β-defensinas. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
El EGCG, presente en el té verde, posee propiedades antiinflamatorias y puede afectar a la expresión de la β-defensina. | ||||||
Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $120.00 $400.00 $569.00 $1465.00 | ||
La lactoferrina, un componente del sistema inmunitario innato, puede modular las respuestas inmunitarias y potencialmente la expresión de β-defensina. |