ZNHIT1 Inhibitors
ZNHIT1, also known as Zinc Finger HIT-Type Containing 1, plays a crucial role in various cellular processes, particularly in transcriptional regulation and chromatin remodeling. As a member of the zinc finger domain-containing protein family, ZNHIT1 is involved in modulating gene expression by interacting with transcription factors and chromatin remodeling complexes. Additionally, ZNHIT1 has been implicated in DNA repair processes, suggesting its importance in maintaining genomic stability. Furthermore, ZNHIT1 has been associated with diverse cellular functions, including cell cycle progression, apoptosis, and development, highlighting its multifaceted roles in cellular homeostasis.
The inhibition of ZNHIT1 involves disrupting its interactions with transcription factors and chromatin remodeling complexes, thereby impeding its ability to modulate gene expression and chromatin structure. Additionally, inhibiting ZNHIT1 may interfere with its involvement in DNA repair processes, leading to compromised genomic stability. Moreover, targeting ZNHIT1 inhibition could potentially affect downstream cellular functions regulated by ZNHIT1, such as cell cycle progression and apoptosis. Overall, elucidating the mechanisms of ZNHIT1 inhibition could provide insights into its physiological functions and may have implications in various biological contexts, including disease pathogenesis.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Interferes with lysosomal acidification, which can affect cellular processes including chromatin dynamics. | ||||||
M 344 | 251456-60-7 | sc-203124 sc-203124A | 1 mg 5 mg | $107.00 $316.00 | 8 | |
Inhibits HDAC, leading to increased acetylation of histones and potential disruption of chromatin assembly processes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
HDAC inhibitor that alters chromatin structure and could indirectly influence ZNHIT1's role in nucleosome assembly. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, potentially disrupting the epigenetic marks that guide ZNHIT1 function. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
A non-nucleoside DNA methyltransferase inhibitor, potentially altering chromatin states and indirectly affecting ZNHIT1. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
An HDAC inhibitor that may perturb chromatin assembly and thus ZNHIT1 function. | ||||||
Homocysteine | 6027-13-0 | sc-507315 | 250 mg | $195.00 | ||
A product inhibitor of methyltransferases, could indirectly affect ZNHIT1 by altering methylation patterns. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 free base | sc-202651 | 5 mg | $148.00 | 4 | |
An inhibitor of G9a and GLP histone methyltransferases, potentially disrupting chromatin marks relevant to ZNHIT1. | ||||||
UNC0638 | 1255580-76-7 | sc-397012 | 10 mg | $315.00 | ||
Targeting the same enzymes as BIX-01294, could affect chromatin structure and ZNHIT1's role. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $120.00 | 5 | |
A specific inhibitor of the histone methyltransferase SUV39H1, potentially influencing chromatin organization. | ||||||