ZNF274 Activators
ZNF274 Activators would constitute a class of chemical compounds that specifically increase the expression or activity of the zinc finger protein 274 (ZNF274). Zinc finger proteins are a broad group of proteins that can bind to DNA, and they are involved in a myriad of cellular functions such as transcriptional regulation, DNA recognition, and repair. ZNF274 is notable for its roles within the cellular framework, particularly concerning telomere maintenance and the regulation of transcriptional processes. Activators of ZNF274 would interact with the cellular machinery to either enhance the production of the ZNF274 protein or increase its functional capability once synthesized. This could be achieved through direct interaction with the ZNF274 gene, its promoter region, or by modulating the cellular signaling pathways that govern its expression. These activators might also work by altering the epigenetic state of the ZNF274 gene, making it more accessible for transcription, or by stabilizing the mRNA to increase protein translation.
The chemical compounds classified as ZNF274 Activators would likely be diverse in structure, reflecting the multiple avenues through which ZNF274 expression can be modulated. One mechanism could involve the inhibition of negative regulatory elements that suppress ZNF274 expression, thereby lifting repression and allowing for increased transcription. Another approach could involve the modification of transcription factors or co-activators that directly interact with the ZNF274 gene, enhancing their affinity or their ability to recruit the transcriptional machinery. Additionally, given the involvement of ZNF274 in chromosomal stability, activators might also target the protein's interaction with chromosomal ends, indirectly promoting its stabilization and function. The study of ZNF274 Activators would be of great interest in understanding the complex network of gene regulation, particularly how specific proteins are fine-tuned in response to intracellular and extracellular signals.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3, through its active metabolite, might engage nuclear receptors influencing the expression of ZNF274. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound, a DNA methyltransferase inhibitor, could induce demethylation of the ZNF274 gene promoter. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As an HDAC inhibitor, Trichostatin A could facilitate a more open chromatin state, potentially upregulating ZNF274. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid may modulate gene expression through its interaction with retinoic acid receptors, affecting ZNF274. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises intracellular cAMP levels, which may alter transcription factor binding and upregulate ZNF274 expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C, which could lead to changes in transcription factor activity and gene expression, including ZNF274. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, through its effects on multiple signaling pathways, might enhance the transcription of genes like ZNF274. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate, an HDAC inhibitor, may enhance ZNF274 expression by causing chromatin decondensation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone can modulate gene expression via glucocorticoid receptor signaling, potentially affecting ZNF274. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, might influence transcriptional regulation, potentially inducing ZNF274. | ||||||