ZNF193 Activators
Chemical activators of Zinc Finger Protein 193 (ZNF193) have diverse mechanisms by which they can induce conformational changes that activate the protein's DNA-binding function. Zinc Chloride is instrumental in providing zinc ions, which are essential for the structural integrity of the zinc finger domains in ZNF193. These domains are critical for the protein's ability to engage with DNA, and zinc ions directly contribute to the maintenance of the conformation required for binding. Magnesium Chloride also plays a pivotal role, as the magnesium ions it supplies contribute to the stability of ZNF193, thus ensuring it retains the necessary shape for DNA interaction. Cobalt(II) Chloride and Nickel(II) Sulfate both supply their respective metal ions, cobalt and nickel, which can bind to the zinc finger motifs. This binding can result in an alternative, yet functional, active configuration of the protein that maintains its ability to interact with DNA.
Cadmium Chloride, Copper(II) Sulfate, and Mercury(II) Chloride each provide metal ions that can associate with the zinc finger domains of ZNF193. Cadmium ions can bind and potentially cause a conformational rearrangement that activates the DNA-binding capability, while copper ions can induce changes that activate the protein's interaction with DNA. Mercury ions are known for their high affinity for the cysteine residues within the zinc finger domains, which can lead to structural modifications conducive to DNA binding. Silver Nitrate supplies silver ions, which may facilitate a structural transition in ZNF193 to an active state that promotes DNA interaction. Additionally, Potassium Dichromate and Sodium Selenite influence the cellular redox state, which in turn affects the metal-binding properties of ZNF193, ensuring the protein adopts a conformation that is amenable to DNA binding. Ferric Chloride and Bismuth(III) Nitrate provide iron and bismuth ions, respectively, which can interact with the protein's zinc finger motifs. Such interaction may promote a structural conformation that favors the activation of ZNF193, enhancing its DNA-binding activity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc Chloride can provide zinc ions necessary for the structural integrity of ZNF193, which contains zinc finger domains crucial for DNA binding. The addition of zinc ions can directly activate the DNA-binding capability of ZNF193 by stabilizing the finger motifs. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $28.00 $35.00 $48.00 $125.00 | 2 | |
Magnesium Chloride contributes magnesium ions, which can improve the stability of zinc finger domains in ZNF193. This stabilization can directly activate ZNF193 by ensuring it maintains the proper conformation necessary for interacting with its DNA targets. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $64.00 $176.00 | 7 | |
Cobalt(II) Chloride provides cobalt ions that can bind to the zinc finger motifs in ZNF193, potentially leading to an alternative active configuration which still enables the protein to functionally interact with DNA, thereby activating ZNF193. | ||||||
Nickel Sulfate | 7786-81-4 | sc-507407 | 5 g | $63.00 | ||
Nickel(II) Sulfate provides nickel ions that can interact with the zinc finger motifs of ZNF193, which may induce a conformational change leading to the functional activation of its DNA binding activity. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $56.00 $183.00 $352.00 | 1 | |
Cadmium Chloride offers cadmium ions that may bind to the zinc finger domains of ZNF193, potentially causing a structural conformation that activates the protein's DNA-binding function. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper(II) Sulfate delivers copper ions, which can interact with the zinc finger motifs of ZNF193, potentially inducing a conformational change that activates the protein's ability to bind to DNA. | ||||||
Silver nitrate | 7761-88-8 | sc-203378 sc-203378A sc-203378B | 25 g 100 g 500 g | $114.00 $378.00 $1081.00 | 1 | |
Silver Nitrate supplies silver ions that could induce a change in the structure of ZNF193, favoring an active state that enhances DNA binding and thereby activates the protein. | ||||||
Sodium selenite | 10102-18-8 | sc-253595 sc-253595B sc-253595C sc-253595A | 5 g 500 g 1 kg 100 g | $49.00 $183.00 $316.00 $98.00 | 3 | |
Sodium Selenite influences the cellular redox environment, which can ensure the proper zinc finger structure of ZNF193 is maintained for active DNA interaction. | ||||||
Iron(III) chloride | 7705-08-0 | sc-215192 sc-215192A sc-215192B | 10 g 100 g 500 g | $41.00 $46.00 $87.00 | ||
Ferric Chloride provides iron ions that can interact with the zinc finger motifs of ZNF193, potentially leading to a conformation that promotes the protein's activation and enhances its interaction with DNA. | ||||||