ZNF175 Activators
ZNF175 activators encompass a range of chemicals that can indirectly modulate the function of the ZNF175 protein, a zinc-finger protein involved in transcription regulation. One prominent method of indirect modulation is through the activation or regulation of signaling pathways that have downstream effects on the protein. For instance, chemicals such as AICAR and Metformin that activate AMPK are believed to support ZNF175's DNA-binding activity through their effects on cellular energy homeostasis. Similarly, activators like PMA that modulate the PKC pathway might affect ZNF175 by influencing the transcriptional machinery associated with it.
Another avenue is through chemicals that influence cAMP levels in cells. Given that ZNF175's activity is tied to transcriptional regulation, fluctuations in cAMP levels introduced by chemicals like Caffeine, IBMX, and 8-Br-cAMP can provide conditions favorable for its function. Meanwhile, substances like Okadaic Acid elevate protein phosphorylation levels, indirectly influencing ZNF175. It's imperative to note that while these chemicals can modulate pathways associated with ZNF175, the exact interactions and effects might vary based on cellular context and other present factors.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR, an activator of AMPK, can indirectly affect ZNF175's DNA-binding activity in relation to energy homeostasis in the cell. By activating AMPK, it enhances cellular processes that might boost the activity of transcription factors such as ZNF175. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin, primarily known for its role in glucose regulation, also activates AMPK. Similar to AICAR, its activation of AMPK can support ZNF175's DNA-binding transcription activity in relation to energy balance within the cell. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
As a PKC activator, PMA can influence the transcriptional machinery associated with proteins like ZNF175. By modulating PKC, it might indirectly affect the DNA-binding and transcriptional activities of ZNF175. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin activates JNK pathway which, when activated, might have cascading effects on proteins such as ZNF175 which are involved in transcription regulation. The specific interaction isn't well-documented but its pathway activation can impact ZNF175 function. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine inhibits phosphodiesterase leading to an increase in cAMP. Elevated cAMP levels may indirectly support ZNF175 activity by modulating associated pathways or cellular processes. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX, a phosphodiesterase inhibitor, elevates cAMP levels which in turn might provide a conducive environment for ZNF175 and its transcriptional activities. Like caffeine, it affects ZNF175 by acting through the cAMP pathway. | ||||||
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $106.00 $166.00 $289.00 $550.00 $819.00 | 2 | |
8-Br-cAMP, a cAMP analog, can modulate cellular processes associated with cAMP. This can indirectly impact ZNF175 by promoting conditions favorable for its DNA-binding and transcriptional activities. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Okadaic Acid, a serine/threonine protein phosphatase inhibitor, can elevate the phosphorylation levels of many proteins. This action can indirectly influence ZNF175 and its role in transcriptional regulation. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 inhibits Rho-associated protein kinase (ROCK). By inhibiting ROCK, pathways associated with cytoskeletal dynamics can be influenced which indirectly might support ZNF175 functions. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $96.00 $334.00 | 50 | |
L-PA, an activator of the LPA1 receptor, can influence various cellular pathways. One of these pathways might indirectly modulate ZNF175 and its associated activities, though the specific interaction isn't well-documented. | ||||||