ZNF142 Activators
Epigenetic modulators such as Epigallocatechin gallate (EGCG), Resveratrol, Curcumin, Sodium Butyrate, Suberoylanilide Hydroxamic Acid, 5-Aza-2'-deoxycytidine, 3-Deazaneplanocin, HCl salt, BIX-01294, and RG108 play pivotal roles in altering the chromatin architecture. They achieve this by regulating the activity of enzymes responsible for adding or removing epigenetic marks like DNA methylation and histone acetylation. EGCG can impact DNA methylation processes, potentially leading to an increase in ZNF142 expression. Similarly, Curcumin and Sodium Butyrate can influence histone acetylation, thereby affecting the chromatin state and possibly enhancing the transcription of ZNF142.
Moreover, compounds that target intracellular signaling cascades, such as Retinoic Acid, PD0325901, and SP600125, indirectly modulate the activity of ZNF142 by impacting the network of transcription factors and co-regulators. Retinoic Acid, for example, interacts with nuclear receptors that may regulate ZNF142 expression. PD0325901 and SP600125 influence the MAPK pathway, affecting transcription factors that could lead to the upregulation of ZNF142.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG can modulate DNA methylation processes, which may lead to changes in the chromatin state and enhance ZNF142 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol can activate sirtuin 1, which may deacetylate histones and affect ZNF142 gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can inhibit histone acetyltransferases, potentially leading to a chromatin conformation that supports ZNF142 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, as a histone deacetylase inhibitor, can cause a more relaxed chromatin structure that may increase ZNF142 transcription. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
SAHA inhibits histone deacetylases, potentially leading to enhanced transcription of ZNF142. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
This DNA methyltransferase inhibitor can lead to hypomethylation of the ZNF142 promoter region, potentially increasing its transcription. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid can regulate gene expression through retinoic acid receptors, which may influence ZNF142 expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125, a JNK inhibitor, can influence AP-1 activity, which may contribute to regulation of ZNF142 expression. | ||||||
3-Deazaneplanocin, HCl salt | 120964-45-6 | sc-351856 sc-351856A sc-351856B | 1 mg 5 mg 10 mg | $256.00 $612.00 $936.00 | 2 | |
DZNep inhibits EZH2, which can lead to reduced histone methylation and potentially upregulate ZNF142 expression. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $37.00 $112.00 $408.00 | ||
BIX-01294 inhibits G9a histone methyltransferase, potentially leading to changes in histone methylation that support ZNF142 expression. | ||||||