ZNF133 Activators
ZNF133 activators encompass a diverse range of compounds that can influence cellular pathways, leading to an increase in the expression or activity of ZNF133 indirectly. These compounds interact with various elements of the cellular machinery, triggering a cascade of events that may culminate in the upregulation of ZNF133. For instance, retinoic acid and compounds like Trichostatin A modulate gene expression through their impact on transcriptional regulation, either by receptor-mediated transcription or by altering the epigenetic state of the genome. Retinoic acid exerts its effects by binding to retinoic acid receptors, which subsequently bind to retinoic acid response elements in the promoters of target genes, potentially including ZNF133. On the other hand, Trichostatin A can increase gene transcription by preventing histone deacetylation, thus relaxing chromatin structure.
Additional compounds, such as Forskolin, PMA, Sodium Butyrate, and Lithium Chloride, function by activating or inhibiting enzymes that regulate transcription factors and gene expression. Forskolin, through elevation of cAMP, initiates a signaling cascade that can lead to transcription
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of Vitamin A that regulates gene expression by activating nuclear retinoid receptors, which can lead to changes in the expression of a broad range of genes, including those encoding zinc finger proteins like ZNF133. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that causes changes in chromatin structure, thereby influencing gene expression. It may activate ZNF133 by inducing a more relaxed chromatin state around its promoter. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An activator of adenylyl cyclase that increases levels of cAMP, a secondary messenger that activates a cascade of protein kinases and can change the transcriptional activity of many genes, potentially including ZNF133. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
An activator of protein kinase C that can modulate transcription factors and gene expression profiles, potentially upregulating ZNF133. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A histone deacetylase inhibitor similar to Trichostatin A, which can lead to a more open chromatin structure and could result in increased expression of ZNF133. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
An inhibitor of glycogen synthase kinase-3 that may alter the signaling pathways and lead to changes in gene expression, including potential upregulation of ZNF133. | ||||||
Kinetin | 525-79-1 | sc-207780 sc-207780A | 1 g 5 g | $38.00 $48.00 | ||
A type of cytokinin plant hormone that has been shown to affect gene expression in mammalian cells. It could potentially influence ZNF133 expression by altering cellular signaling and transcriptional control. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound found in turmeric that can modulate various signaling pathways and affect gene expression, potentially increasing ZNF133 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenolic compound that activates sirtuins and modulates multiple cellular pathways, potentially leading to upregulation of genes including ZNF133. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Provides zinc ions, which are essential for the structural integrity and DNA-binding capability of zinc finger proteins; supplemental zinc can enhance the function of zinc finger proteins like ZNF133. | ||||||