ZADH1 Inhibitors
ZADH1 inhibitors encompass a series of chemicals that predominantly target enzymes related to alcohol or aldehyde metabolism. Given that ZADH1 is categorized under the alcohol dehydrogenase domain-containing proteins, chemicals like 4-Methylpyrazole, Fomepizole, and Disulfiram can influence its enzymatic activity due to their established inhibitory effects on related enzymes. These compounds, by broadly targeting this enzyme class, provide avenues to modulate ZADH1 function.
Compounds like Cyanamide, Chlorpropamide, and Daidzin, known to primarily target aldehyde dehydrogenase, signify another group of molecules that can indirectly affect ZADH1 functionality. Additionally, enzyme modulators like Propargylamine and Hydroxylamine, with their general enzyme inhibition capabilities, present interactions with ZADH1. Notably, certain compounds, such as D-penicillamine and Pyrithione, can interfere with zinc-binding, and given ZADH1's zinc-binding domain, these agents provide a unique approach to influencing the protein's functionality.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Known to inhibit aldehyde dehydrogenase but can potentially affect ZADH1 given its broader enzyme inhibition profile. | ||||||
Fomepizole | 7554-65-6 | sc-252838 | 1 g | $75.00 | 1 | |
Primarily an alcohol dehydrogenase inhibitor; its effect on ZADH1 is due to the broad inhibition of this enzyme class. | ||||||
Cyanamide | 420-04-2 | sc-239592 sc-239592A | 5 g 25 g | $21.00 $79.00 | ||
Another aldehyde dehydrogenase inhibitor that can influence ZADH1 indirectly. | ||||||
Propargyl alcohol | 107-19-7 | sc-224210 sc-224210A | 100 ml 500 ml | $27.00 $37.00 | ||
Inhibits monoamine oxidase but given its enzyme inhibition profile, it can have an influence on ZADH1. | ||||||
Hydroxylamine solution | 7803-49-8 | sc-250136 | 100 ml | $72.00 | ||
A general enzyme inhibitor that can potentially impact ZADH1's function. | ||||||
Chlorpropamide | 94-20-2 | sc-234350 | 25 g | $73.00 | 7 | |
Aldehyde dehydrogenase inhibitor; its broad action can influence ZADH1 indirectly. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Known for inhibiting various enzymes, this flavonoid may affect ZADH1 functionality indirectly. | ||||||
Daidzin | 552-66-9 | sc-202123 sc-202123A | 1 mg 5 mg | $72.00 $137.00 | 1 | |
An isoflavone that inhibits aldehyde dehydrogenase, potentially affecting ZADH1. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
While mainly targeting NRF2 pathway, it can have broader enzyme inhibition effects, including potential effects on ZADH1. | ||||||
Penicillamine | 52-67-5 | sc-205795 sc-205795A | 1 g 5 g | $46.00 $96.00 | ||
Can chelate zinc, potentially affecting the functionality of zinc-binding proteins like ZADH1. | ||||||