Date published: 2025-12-19

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XRCC Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of XRCC monoclonal antibodies for research in DNA repair mechanisms. XRCC monoclonal antibodies are effective tools for various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). XRCC proteins play a crucial role in the repair of DNA damage, particularly in maintaining genomic stability and preventing mutations that can lead to cancer. The involvement of XRCC proteins in the cellular response to DNA damage makes XRCC monoclonal antibodies essential for studies focused on cancer biology, genetic disorders, and the mechanisms of cellular repair processes. Understanding XRCC protein function is vital for advancing therapeutic strategies and improving knowledge of cellular responses to genotoxic stress. Researchers worldwide rely on XRCC monoclonal antibodies to uncover new insights into DNA repair pathways and their impact on human health. XRCC monoclonal antibodies enable detailed investigation of repair mechanisms at the molecular level, supporting breakthrough discoveries in genome maintenance and stability. Santa Cruz Biotechnology monoclonal antibodies continue to support scientific advancement by providing reliable tools for researchers studying fundamental cellular processes.

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XRCC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

XRCC1 Antibody (AP-39)

sc-517377mouse IgG1(h)WB, IPh

new

(0)

XRCC2 Antibody (F-4)

sc-365854mouse IgG2a κ6-33 (h)WB, IP, IF, ELISAm, r, h
12
(2)

XRCC2 Antibody (1G4/1)

sc-53469mouse IgG1 κ(h)WB, IPh and hamster

new

(1)

XRCC2 Antibody (3C190)

sc-73278mouse IgG1(h)WBh
1
(1)

XRCC2 Antibody (7B7/3)

sc-53470mouse IgG1(h)WBh

new

(1)

XRCC3 Antibody (D-7)

sc-271714mouse IgG2a κ1-300 (h)WB, IP, IF, ELISAh
9
(1)

XRCC3 Antibody (10F1/6)

sc-53471mouse IgG1 κ(h)WB, IPh
4
(2)

XRCC4 Antibody (C-4)

sc-271087mouse IgG2a κ1-233 (h)WB, IP, IF, IHC(P), ELISAm, r, h
28
(13)

XRCC4 Antibody (A-7)

sc-365055mouse IgG2b κ307-337 (h)WB, IP, IF, ELISAm, r, h
5
(4)

XRCC4 Antibody (G-10)

sc-365118mouse IgG1 κ307-337 (h)WB, IP, IF, ELISAm, r, h
2
(2)

XRCC4 Antibody (4)

sc-136124mouse IgG2b53-168 (h)WB, IP, IFh

new

(3)

XRCC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XRCC1 CRISPR/Cas9 KO Plasmid (h)

sc-401784hGene KnockoutGFP0
(0)

XRCC1 HDR Plasmid (h)

sc-401784-HDRhHomology Directed RepairPuromycin0
(0)

XRCC1 Double Nickase Plasmid (h)

sc-401784-NIChGene KnockoutPuromycin0
(0)

XRCC1 Double Nickase Plasmid (h2)

sc-401784-NIC-2hGene KnockoutPuromycin0
(0)

XRCC1 CRISPR/Cas9 KO Plasmid (m)

sc-423738mGene KnockoutGFP0
(0)

XRCC1 HDR Plasmid (m)

sc-423738-HDRmHomology Directed RepairPuromycin0
(0)

XRCC1 Double Nickase Plasmid (m)

sc-423738-NICmGene KnockoutPuromycin0
(0)

XRCC1 Double Nickase Plasmid (m2)

sc-423738-NIC-2mGene KnockoutPuromycin0
(0)

XRCC2 CRISPR/Cas9 KO Plasmid (h)

sc-403531hGene KnockoutGFP0
(0)

XRCC2 CRISPR/Cas9 KO Plasmid (h2)

sc-403531-KO-2hGene KnockoutGFP0
(0)

XRCC2 HDR Plasmid (h2)

sc-403531-HDR-2hHomology Directed RepairPuromycin0
(0)

XRCC2 Double Nickase Plasmid (h)

sc-403531-NIChGene KnockoutPuromycin0
(0)

XRCC2 Double Nickase Plasmid (h2)

sc-403531-NIC-2hGene KnockoutPuromycin0
(0)

XRCC2 CRISPR/Cas9 KO Plasmid (m)

sc-425403mGene KnockoutGFP0
(0)

XRCC2 HDR Plasmid (m)

sc-425403-HDRmHomology Directed RepairPuromycin0
(0)

XRCC2 Double Nickase Plasmid (m)

sc-425403-NICmGene KnockoutPuromycin0
(0)

XRCC2 Double Nickase Plasmid (m2)

sc-425403-NIC-2mGene KnockoutPuromycin0
(0)

XRCC3 CRISPR/Cas9 KO Plasmid (h)

sc-405570hGene KnockoutGFP0
(0)

XRCC3 HDR Plasmid (h)

sc-405570-HDRhHomology Directed RepairPuromycin0
(0)

XRCC3 Double Nickase Plasmid (h)

sc-405570-NIChGene KnockoutPuromycin0
(0)

XRCC3 Double Nickase Plasmid (h2)

sc-405570-NIC-2hGene KnockoutPuromycin0
(0)

XRCC3 CRISPR/Cas9 KO Plasmid (m)

sc-428841mGene KnockoutGFP0
(0)

XRCC3 HDR Plasmid (m)

sc-428841-HDRmHomology Directed RepairPuromycin0
(0)

XRCC3 Double Nickase Plasmid (m)

sc-428841-NICmGene KnockoutPuromycin0
(0)

XRCC3 Double Nickase Plasmid (m2)

sc-428841-NIC-2mGene KnockoutPuromycin0
(0)

XRCC4 CRISPR/Cas9 KO Plasmid (h)

sc-417614hGene KnockoutGFP0
(0)

XRCC4 HDR Plasmid (h)

sc-417614-HDRhHomology Directed RepairPuromycin0
(0)

XRCC4 Double Nickase Plasmid (h)

sc-417614-NIChGene KnockoutPuromycin0
(0)

XRCC4 Double Nickase Plasmid (h2)

sc-417614-NIC-2hGene KnockoutPuromycin0
(0)

XRCC4 CRISPR/Cas9 KO Plasmid (m)

sc-430821mGene KnockoutGFP0
(0)

XRCC4 HDR Plasmid (m)

sc-430821-HDRmHomology Directed RepairPuromycin0
(0)

XRCC4 Double Nickase Plasmid (m)

sc-430821-NICmGene KnockoutPuromycin0
(0)

XRCC4 Double Nickase Plasmid (m2)

sc-430821-NIC-2mGene KnockoutPuromycin0
(0)

XRCC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XRCC1 CRISPR Activation Plasmid (h)

sc-401784-ACThGene ActivationPuro, Blast, Hygro0
(0)

XRCC1 CRISPR Activation Plasmid (h2)

sc-401784-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

XRCC1 Lentiviral Activation Particles (h)

sc-401784-LAChGene ActivationPuro, Blast, Hygro0
(0)

XRCC1 Lentiviral Activation Particles (h2)

sc-401784-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

XRCC1 CRISPR Activation Plasmid (m)

sc-423738-ACTmGene ActivationPuro, Blast, Hygro0
(0)

XRCC1 CRISPR Activation Plasmid (m2)

sc-423738-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

XRCC1 Lentiviral Activation Particles (m)

sc-423738-LACmGene ActivationPuro, Blast, Hygro0
(0)

XRCC1 Lentiviral Activation Particles (m2)

sc-423738-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

XRCC2 CRISPR Activation Plasmid (h)

sc-403531-ACThGene ActivationPuro, Blast, Hygro0
(0)

XRCC2 CRISPR Activation Plasmid (h2)

sc-403531-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

XRCC2 Lentiviral Activation Particles (h)

sc-403531-LAChGene ActivationPuro, Blast, Hygro0
(0)

XRCC2 Lentiviral Activation Particles (h2)

sc-403531-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

XRCC2 CRISPR Activation Plasmid (m)

sc-425403-ACTmGene ActivationPuro, Blast, Hygro0
(0)

XRCC2 CRISPR Activation Plasmid (m2)

sc-425403-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

XRCC2 Lentiviral Activation Particles (m)

sc-425403-LACmGene ActivationPuro, Blast, Hygro0
(0)

XRCC2 Lentiviral Activation Particles (m2)

sc-425403-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

XRCC3 CRISPR Activation Plasmid (h)

sc-405570-ACThGene ActivationPuro, Blast, Hygro0
(0)

XRCC3 CRISPR Activation Plasmid (h2)

sc-405570-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

XRCC3 Lentiviral Activation Particles (h)

sc-405570-LAChGene ActivationPuro, Blast, Hygro0
(0)

XRCC3 Lentiviral Activation Particles (h2)

sc-405570-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

XRCC3 CRISPR Activation Plasmid (m)

sc-428841-ACTmGene ActivationPuro, Blast, Hygro0
(0)

XRCC3 CRISPR Activation Plasmid (m2)

sc-428841-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

XRCC3 Lentiviral Activation Particles (m)

sc-428841-LACmGene ActivationPuro, Blast, Hygro0
(0)

XRCC3 Lentiviral Activation Particles (m2)

sc-428841-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

XRCC4 CRISPR Activation Plasmid (h)

sc-417614-ACThGene ActivationPuro, Blast, Hygro0
(0)

XRCC4 CRISPR Activation Plasmid (h2)

sc-417614-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

XRCC4 Lentiviral Activation Particles (h)

sc-417614-LAChGene ActivationPuro, Blast, Hygro0
(0)

XRCC4 Lentiviral Activation Particles (h2)

sc-417614-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

XRCC4 CRISPR Activation Plasmid (m)

sc-430821-ACTmGene ActivationPuro, Blast, Hygro0
(0)

XRCC4 CRISPR Activation Plasmid (m2)

sc-430821-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

XRCC4 Lentiviral Activation Particles (m)

sc-430821-LACmGene ActivationPuro, Blast, Hygro0
(0)

XRCC4 Lentiviral Activation Particles (m2)

sc-430821-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

XRCC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XRCC1 siRNA (h)

sc-36859hGene SilencingN/A
7
(0)

XRCC1 shRNA Plasmid (h)

sc-36859-SHhGene SilencingPuromycin
7
(0)

XRCC1 shRNA (h) Lentiviral Particles

sc-36859-VhGene SilencingPuromycin
7
(0)

XRCC1 siRNA (m)

sc-36860mGene SilencingN/A0
(0)

XRCC1shRNA (m) shRNA (m) Lentiviral Particles

sc-36860-VmGene SilencingPuromycin0
(0)

XRCC1shRNA Plasmid (m)-SH shRNA Plasmid (m)

sc-36860-SHmGene SilencingPuromycin0
(0)

XRCC2 siRNA (h)

sc-36861hGene SilencingN/A
2
(0)

XRCC2 shRNA Plasmid (h)

sc-36861-SHhGene SilencingPuromycin
2
(0)

XRCC2 shRNA (h) Lentiviral Particles

sc-36861-VhGene SilencingPuromycin
2
(0)

XRCC2 siRNA (m)

sc-36862mGene SilencingN/A0
(0)

XRCC2 shRNA Plasmid (m)

sc-36862-SHmGene SilencingPuromycin0
(0)

XRCC2 shRNA (m) Lentiviral Particles

sc-36862-VmGene SilencingPuromycin0
(0)

XRCC3 siRNA (h)

sc-37403hGene SilencingN/A0
(0)

XRCC3 shRNA Plasmid (h)

sc-37403-SHhGene SilencingPuromycin0
(0)

XRCC3 shRNA (h) Lentiviral Particles

sc-37403-VhGene SilencingPuromycin0
(0)

XRCC3 siRNA (m)

sc-37404mGene SilencingN/A0
(0)

XRCC3 shRNA Plasmid (m)

sc-37404-SHmGene SilencingPuromycin0
(0)

XRCC3 shRNA (m) Lentiviral Particles

sc-37404-VmGene SilencingPuromycin0
(0)

XRCC4 siRNA (h)

sc-37405hGene SilencingN/A
5
(0)

XRCC4 shRNA Plasmid (h)

sc-37405-SHhGene SilencingPuromycin
5
(0)

XRCC4 shRNA (h) Lentiviral Particles

sc-37405-VhGene SilencingPuromycin
5
(0)

XRCC4 siRNA (m)

sc-37406mGene SilencingN/A
1
(0)

XRCC4 shRNA Plasmid (m)

sc-37406-SHmGene SilencingPuromycin
1
(0)

XRCC4 shRNA (m) Lentiviral Particles

sc-37406-VmGene SilencingPuromycin
1
(0)