Date published: 2025-10-25

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Wnt-2 Inhibitors

Wnt-2 inhibitors belong to a specific chemical class of compounds that have been studied and designed to selectively target and inhibit the activity of Wnt-2, a member of the Wnt family of secreted glycoproteins. Wnt-2 plays critical roles in cell signaling and development, including processes like cell proliferation, differentiation, and tissue patterning. Inhibition of Wnt-2 aims to disrupt its signaling pathway and potentially modulate various cellular processes that rely on Wnt-2-mediated signaling. The chemical structures of Wnt-2 inhibitors can vary, including small-molecule compounds and specific inhibitors that target key components of the Wnt signaling pathway.

Researchers have explored various strategies to target Wnt-2 and attenuate its effects on cellular signaling. The study of Wnt-2 inhibitors provides valuable insights into the intricate regulatory mechanisms governing cell development and tissue homeostasis. Continued research in this chemical class holds promise for advancing our understanding of Wnt-2's role in cellular physiology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

IWP-2

686770-61-6sc-252928
sc-252928A
5 mg
25 mg
$94.00
$286.00
27
(1)

This is a small-molecule compound that has been investigated for its potential to inhibit Wnt signaling, including Wnt-2.

XAV939

284028-89-3sc-296704
sc-296704A
sc-296704B
1 mg
5 mg
50 mg
$35.00
$115.00
$515.00
26
(1)

Another small-molecule inhibitor, XAV939, has shown inhibitory effects on Wnt-2 signaling.

LGK 974

1243244-14-5sc-489380
sc-489380A
5 mg
50 mg
$352.00
$1270.00
2
(0)

This is a specific inhibitor of the Wnt palmitoyltransferase porcupine, which is involved in the acylation of Wnt-2 and other Wnt proteins.

Salinomycin

53003-10-4sc-253530
sc-253530C
sc-253530A
sc-253530B
5 mg
10 mg
25 mg
100 mg
$159.00
$236.00
$398.00
$465.00
1
(1)

Salinomycin has been studied for its potential to inhibit Wnt-2-induced cancer stem cell growth.

PRI-724

1422253-38-0sc-507535
25 mg
$255.00
(0)

This compound targets the interaction between Wnt-2 and the transcriptional coactivator β-catenin.