Wnt-2 inhibitors belong to a specific chemical class of compounds that have been studied and designed to selectively target and inhibit the activity of Wnt-2, a member of the Wnt family of secreted glycoproteins. Wnt-2 plays critical roles in cell signaling and development, including processes like cell proliferation, differentiation, and tissue patterning. Inhibition of Wnt-2 aims to disrupt its signaling pathway and potentially modulate various cellular processes that rely on Wnt-2-mediated signaling. The chemical structures of Wnt-2 inhibitors can vary, including small-molecule compounds and specific inhibitors that target key components of the Wnt signaling pathway.
Researchers have explored various strategies to target Wnt-2 and attenuate its effects on cellular signaling. The study of Wnt-2 inhibitors provides valuable insights into the intricate regulatory mechanisms governing cell development and tissue homeostasis. Continued research in this chemical class holds promise for advancing our understanding of Wnt-2's role in cellular physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $94.00 $286.00 | 27 | |
This is a small-molecule compound that has been investigated for its potential to inhibit Wnt signaling, including Wnt-2. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $35.00 $115.00 $515.00 | 26 | |
Another small-molecule inhibitor, XAV939, has shown inhibitory effects on Wnt-2 signaling. | ||||||
LGK 974 | 1243244-14-5 | sc-489380 sc-489380A | 5 mg 50 mg | $352.00 $1270.00 | 2 | |
This is a specific inhibitor of the Wnt palmitoyltransferase porcupine, which is involved in the acylation of Wnt-2 and other Wnt proteins. | ||||||
Salinomycin | 53003-10-4 | sc-253530 sc-253530C sc-253530A sc-253530B | 5 mg 10 mg 25 mg 100 mg | $159.00 $236.00 $398.00 $465.00 | 1 | |
Salinomycin has been studied for its potential to inhibit Wnt-2-induced cancer stem cell growth. | ||||||
PRI-724 | 1422253-38-0 | sc-507535 | 25 mg | $255.00 | ||
This compound targets the interaction between Wnt-2 and the transcriptional coactivator β-catenin. | ||||||