WDR17 activators belong to a specialized chemical class known for their ability to modulate the activity of WDR17, a protein encoded by the WDR17 gene. WDR17, also known as WD repeat-containing protein 17, is a member of the WD40 repeat protein family, which plays diverse roles in cellular processes such as signal transduction, protein-protein interactions, and chromatin remodeling. While the precise function of WDR17 is still being elucidated, studies suggest its involvement in various biological processes, including mRNA splicing, ribosome biogenesis, and cytoskeletal organization. Activators targeting WDR17 exert their effects by potentially influencing its protein-protein interactions, subcellular localization, or post-translational modifications. These activators are essential for understanding the biological functions of WDR17 and its contributions to cellular physiology.
Structurally, WDR17 activators may exhibit a diverse range of chemical scaffolds, reflecting the complexity required for effective engagement with the target protein. These molecules may possess specific binding motifs or functional groups that facilitate their interaction with WDR17, enabling them to modulate its activity with precision. Understanding the structural and biochemical properties of WDR17 activators is crucial for unraveling the molecular mechanisms underlying the functions of this protein and its involvement in cellular processes. Further exploration of the pharmacological characteristics and biological significance of WDR17 activators holds promise for advancing our understanding of cellular physiology and may offer insights into novel strategies for manipulating cellular functions in various biological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Could increase WDR17 expression by elevating cAMP levels, affecting transcriptional regulation through CREB activation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Might influence WDR17 expression through its role in cellular differentiation, potentially involving changes in gene transcription. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As a histone deacetylase inhibitor, might enhance WDR17 expression by increasing chromatin accessibility for transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Another histone deacetylase inhibitor, TSA may upregulate WDR17 by altering chromatin structure and facilitating gene expression. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
May induce WDR17 expression as part of the oxidative stress response, potentially involving redox-sensitive transcription factors. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Could modulate WDR17 expression through vitamin D receptor-mediated transcriptional regulation, affecting cell growth and differentiation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Might affect WDR17 expression by inhibiting mTOR signaling, which is involved in protein synthesis and cell growth regulation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
May influence WDR17 expression through its anti-inflammatory effects and modulation of signaling pathways. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that could upregulate WDR17 by demethylating DNA and activating gene transcription. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
As a hormone, beta-estradiol could modulate WDR17 expression through estrogen receptor-mediated signaling pathways. | ||||||