WDFY2 Activators
The chemical class of WDFY2 activators comprises a diverse set of compounds that intricately modulate cellular pathways to stimulate WDFY2 activity. One notable activator within this class is Torin 1, which achieves this by inhibiting mTOR. The inhibition of mTOR by Torin 1 enhances autophagy, promoting the recruitment of WDFY2 to autophagic vesicles. This recruitment facilitates WDFY2's role in autophagy-related processes, showcasing the precise modulation of cellular pathways to stimulate WDFY2 activity. Rapamycin, Lithium chloride, Everolimus, A-769662, Trehalose, PP242, SB 216763, AZD8055, Pifithrin-μ, SBI-0206965, and NSC 319726 represent a diverse array of WDFY2 activators that collectively illustrate the intricate ways in which WDFY2 activity can be modulated to enhance autophagy. Rapamycin, for example, is well-known for its mTOR inhibition, similarly promoting autophagy and WDFY2 recruitment. Lithium chloride, on the other hand, influences the autophagic pathway through alternative mechanisms, collectively contributing to the activation of WDFY2.
Everolimus, A-769662, and PP242 further exemplify the diversity within this class, each utilizing unique mechanisms to enhance autophagy and WDFY2 activity. Trehalose, a natural disaccharide, has been shown to induce autophagy, contributing to the overall activation of WDFY2. The presence of SB 216763, AZD8055, Pifithrin-μ, SBI-0206965, and NSC 319726 in this list further emphasizes the intricate ways in which WDFY2 can be modulated, providing valuable insights into potential strategies for manipulating cellular processes. In summary, the diverse set of WDFY2 activators, including Torin 1 and the mentioned compounds, collectively illustrates the intricate modulation of cellular pathways to stimulate WDFY2 activity and enhance autophagy-related processes. These activators offer valuable insights into potential strategies for manipulating cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $245.00 | 7 | |
Torin 1 activates WDFY2 by inhibiting mTOR, promoting autophagy. The enhanced autophagic flux facilitates the recruitment of WDFY2 to autophagic vesicles, promoting its role in autophagy-related processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin activates WDFY2 by inhibiting mTOR, enhancing autophagy. The increased autophagic flux promotes the recruitment of WDFY2 to autophagic vesicles, facilitating its involvement in autophagy-related processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride activates WDFY2 by inhibiting GSK-3β, promoting autophagy. The enhanced autophagic flux facilitates the recruitment of WDFY2 to autophagic vesicles, promoting its role in autophagy-related processes. | ||||||
Everolimus | 159351-69-6 | sc-218452 sc-218452A | 5 mg 50 mg | $131.00 $651.00 | 7 | |
Everolimus activates WDFY2 by inhibiting mTOR, promoting autophagy. The increased autophagic flux facilitates the recruitment of WDFY2 to autophagic vesicles, promoting its involvement in autophagy-related processes. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $184.00 $741.00 $1076.00 $3417.00 $5304.00 | 23 | |
A-769662 activates WDFY2 by inhibiting AMPK, promoting autophagy. The enhanced autophagic flux facilitates the recruitment of WDFY2 to autophagic vesicles, promoting its role in autophagy-related processes. | ||||||
D-(+)-Trehalose Anhydrous | 99-20-7 | sc-294151 sc-294151A sc-294151B | 1 g 25 g 100 g | $30.00 $167.00 $260.00 | 2 | |
Trehalose activates WDFY2 by enhancing autophagy. The increased autophagic flux promotes the recruitment of WDFY2 to autophagic vesicles, facilitating its involvement in autophagy-related processes. | ||||||
PP242 | 1092351-67-1 | sc-301606A sc-301606 | 1 mg 5 mg | $57.00 $172.00 | 8 | |
PP242 activates WDFY2 by inhibiting mTOR, promoting autophagy. The enhanced autophagic flux facilitates the recruitment of WDFY2 to autophagic vesicles, promoting its role in autophagy-related processes. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
SB 216763 activates WDFY2 by inhibiting GSK-3β, promoting autophagy. The enhanced autophagic flux facilitates the recruitment of WDFY2 to autophagic vesicles, promoting its involvement in autophagy-related processes. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $163.00 $352.00 | 12 | |
AZD8055 activates WDFY2 by inhibiting mTOR, promoting autophagy. The increased autophagic flux facilitates the recruitment of WDFY2 to autophagic vesicles, promoting its role in autophagy-related processes. | ||||||
Pifithrin-μ | 64984-31-2 | sc-203195 sc-203195A | 10 mg 50 mg | $130.00 $379.00 | 4 | |
Pifithrin-μ activates WDFY2 by inhibiting p53, promoting autophagy. The enhanced autophagic flux facilitates the recruitment of WDFY2 to autophagic vesicles, promoting its involvement in autophagy-related processes. | ||||||