VWA5A inhibitors belong to a specialized class of chemical compounds designed to target the VWA5A (Von Willebrand Factor A Domain Containing 5A) protein. VWA5A, also known as VWA5A1, is a relatively less characterized protein that contains a Von Willebrand Factor A (VWA) domain. The VWA domain is a structural motif found in various proteins involved in cell adhesion, extracellular matrix organization, and protein-protein interactions. While the precise functions of VWA5A are still under investigation, its VWA domain suggests roles in mediating protein interactions, cellular adhesion, or tissue organization.
Inhibitors of VWA5A are designed to interact with this protein and disrupt its functions or interactions with other molecules. These inhibitors may operate through various mechanisms, such as binding to specific regions of VWA5A or altering its conformation. By inhibiting VWA5A, these compounds can interfere with its involvement in cellular processes related to adhesion, extracellular matrix dynamics, or protein interactions. Research on VWA5A inhibitors is primarily focused on elucidating the molecular functions and roles of VWA5A in various cellular contexts, offering insights into its contributions to cell adhesion and tissue organization, as well as the development of research tools for studying its functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
A compound that binds to DNA and inhibits RNA synthesis, potentially reducing the expression of many genes, including VWA5A. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
A compound that can inhibit RNA polymerase, potentially decreasing the transcription of various genes. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
A potent inhibitor of RNA polymerase II, which could lead to a reduction in mRNA synthesis for many genes. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
A diterpene triepoxide that can inhibit the transcription of a wide range of genes by affecting multiple transcription factors. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
A compound that forms DNA adducts, potentially affecting the transcription of genes by impeding RNA polymerase. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
A compound that binds to DNA and inhibits RNA polymerase, affecting gene expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Acompound known to intercalate into DNA, which may affect DNA replication and gene expression. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
A compound that cross-links DNA, potentially affecting RNA synthesis and gene expression. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
A topoisomerase inhibitor that can lead to DNA damage and potentially alter transcriptional profiles of cells. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
An inhibitor of DNA topoisomerase I, which can interfere with DNA replication and transcription processes. | ||||||