Date published: 2026-4-21

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VSTM2B Activators

VSTM2B activators are a class of chemical compounds that interact with the V-set and transmembrane domain-containing 2B (VSTM2B) protein. This protein is a member of a broader family of V-set domain-containing proteins, which typically have roles in cell adhesion, immune responses, and receptor signaling. The precise function of VSTM2B is not entirely clear, but it is known to be expressed in various tissues throughout the body. Activators of this protein influence its activity, affecting its normal function or interactions within the cellular environment. They may bind to the protein at specific sites, leading to conformational changes that can impact the way VSTM2B interacts with other molecules or carries out its role within cells.

The study of VSTM2B activators encompasses the exploration of their structure, the nature of their interaction with VSTM2B, and the resulting biochemical consequences within cells. These compounds can be small molecules or larger biomolecules that have been identified to have an affinity for the VSTM2B protein. In a laboratory setting, researchers might use various assays and techniques such as ligand binding studies, X-ray crystallography, or nuclear magnetic resonance (NMR) spectroscopy to understand how these activators bind to VSTM2B and to map the precise interactions at the molecular level. By elucidating the molecular details of these interactions, scientists can gain insights into the role of VSTM2B and how its function is modulated. Such knowledge is crucial for a fundamental understanding of the biochemical pathways that VSTM2B is involved in and how its activity affects cellular processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin may elevate cAMP, which could potentially enhance the transcription of a wide range of genes, including VSTM2B.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid can affect gene expression via retinoic acid receptors, possibly impacting VSTM2B transcription.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

This histone deacetylase inhibitor may open chromatin, potentially increasing the expression of genes such as VSTM2B.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

As a DNA methyltransferase inhibitor, it may derepress silenced genes, potentially leading to higher VSTM2B expression.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

May interact with estrogen receptors, influencing gene expression and potentially upregulating VSTM2B.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

As a glucocorticoid, it could influence various gene expression patterns, including possibly VSTM2B's.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C, which might lead to transcriptional changes affecting VSTM2B expression.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium affects multiple signaling pathways, such as GSK-3 inhibition, which might impact gene expression, including VSTM2B.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

This compound may activate Nrf2, potentially regulating the expression of various genes, which could include VSTM2B.