Vmn1r113 Activators
Vmn1r113, a vomeronasal receptor, stands as a pivotal player in the intricate landscape of chemosensory signaling pathways. Functionally, this receptor is dedicated to the detection and transduction of chemical cues, particularly those emanating from the external environment. Positioned within the vomeronasal organ, Vmn1r113 contributes significantly to the modulation of cellular processes driven by chemosensory stimuli. Its primary role lies in recognizing specific ligands and initiating signaling cascades that culminate in diverse cellular responses. The target's function extends beyond a mere molecular sensor; it serves as a molecular gatekeeper, enabling organisms to perceive and respond to chemosensory cues critical for various physiological and behavioral processes.
Activation of Vmn1r113 is orchestrated through a sophisticated interplay of intricate cellular and biochemical mechanisms. Ligand binding to the receptor sets off a cascade of events that involve downstream effectors, including but not limited to cAMP, calcium ions, and protein kinases. These effectors act as mediators, transducing the initial chemical signal into a cellular response. The specificity of Vmn1r113 activation is underscored by the diverse range of chemicals that influence its activity, as exemplified by the compounds outlined in the provided table. From modulating TRPV1 receptors to impacting gene expression and protein kinase activity, the activation mechanisms intricately navigate the molecular landscape, reflecting the precision and specificity inherent in chemosensory signaling. These cascades of events collectively contribute to the receptor's ability to decode and transmit chemosensory information, highlighting the intricate orchestration required for the functioning of Vmn1r113 in cellular contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin, an agonist of TRPV1 receptors, indirectly activates Vmn1r113 by enhancing intracellular calcium levels. This elevation in calcium triggers downstream signaling cascades, impacting cellular processes linked to Vmn1r113 activation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a derivative of vitamin A, indirectly activates Vmn1r113 by modulating gene expression. It affects transcription factors related to Vmn1r113, influencing cellular processes and ultimately leading to the activation of the receptor. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2, acting through EP2 receptors, indirectly influences Vmn1r113 by altering intracellular signaling pathways. This chemical induces cAMP production and activates protein kinase A, contributing to cellular responses associated with Vmn1r113 activation. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
Sodium nitroferricyanide(III) dihydrate, a nitric oxide donor, indirectly activates Vmn1r113 by modulating NO-sensitive signaling pathways. Nitric oxide, produced upon chemical decomposition, influences cellular processes linked to Vmn1r113 activation, mediating downstream effects on the receptor. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A, a protein phosphatase inhibitor, indirectly activates Vmn1r113 by modulating phosphorylation states. This compound disrupts phosphatase activity, affecting cellular processes linked to Vmn1r113 activation. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
8-Bromo-cAMP, a cAMP analog, directly activates Vmn1r113 by mimicking the effects of endogenous cAMP. This chemical enhances intracellular cAMP levels, leading to the activation of the cAMP-dependent pathway associated with Vmn1r113. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187, a calcium ionophore, indirectly activates Vmn1r113 by elevating intracellular calcium concentrations. This chemical impacts downstream signaling cascades, influencing cellular responses associated with Vmn1r113 activation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA, a PKC activator, directly activates Vmn1r113 through the PKC-dependent pathway. This compound stimulates protein kinase C, influencing cellular responses associated with Vmn1r113 activity. | ||||||
WP1130 | 856243-80-6 | sc-364650 sc-364650A | 10 mg 50 mg | $490.00 $1484.00 | 1 | |
WP1130, an inhibitor of glycogen synthase kinase-3, indirectly activates Vmn1r113 by modulating downstream signaling pathways. This chemical alters GSK-3 activity, impacting cellular processes linked to Vmn1r113 activation. | ||||||