V1RD11 Inhibitors
V1RD11 inhibitors encompass a diverse array of chemical compounds that target specific signaling pathways and cellular processes to reduce the functional activity of V1RD11. Alprenolol and Losartan act by antagonizing beta-adrenergic and angiotensin II type 1 receptors, respectively, which can decrease cAMP levels and block signaling cascades that V1RD11 may be associated with, leading to its functional inhibition. Inhibitors like Rapamycin and LY294002 exert their effects by targeting components of the mTOR and PI3K/Akt pathways, respectively, which are potentially linked to V1RD11's role in protein synthesis, cell proliferation, and survival.
Similarly, SB203580, PD98059, and U0126 are inhibitors of different kinases in the MAPK signaling pathways; by blocking p38 MAPK, MEK1/2, and subsequently ERK1/2 activation, these compounds may interfere with V1RD11's influence on cellular stress responses, growth, and differentiation. BAPTA-AM operates by chelating intracellular calcium, a crucial secondary messenger that could be instrumental in V1RD11-mediated signaling. Further expanding the repertoire of V1RD11 inhibitors are compounds like WZ4002, GW5074, SP600125, and Dorsomorphin, each targeting distinct kinases involved in cellular signaling networks. WZ4002 inhibits EGFR, potentially affecting V1RD11-related pathways that control cell proliferation and survival. GW5074 targets RAF kinases, which could disrupt downstream signaling events modulated by V1RD11.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Alprenolol | 13655-52-2 | sc-507469 | 50 mg | $130.00 | ||
Beta-adrenergic blocker that inhibits V1RD11 activity by blocking beta-adrenergic receptors which V1RD11 may be associated with, leading to decreased cAMP levels and reduced V1RD11 signaling. | ||||||
Losartan | 114798-26-4 | sc-353662 | 100 mg | $127.00 | 18 | |
Angiotensin II receptor antagonist that inhibits V1RD11 by blocking the angiotensin II type 1 receptor (AT1R) that could be involved in V1RD11's signaling, reducing its downstream effects. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor that can suppress V1RD11 function by inhibiting the mTOR pathway which V1RD11 could influence, leading to decreased protein synthesis and cell proliferation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor that indirectly diminishes V1RD11 signaling by preventing PI3K/Akt pathway activation, potentially reducing V1RD11-mediated cellular responses. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor that can impede V1RD11 function by inhibiting p38 MAPK, which may be a downstream target of V1RD11 signaling, affecting cellular stress responses. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor that prevents V1RD11 activation by blocking MEK1/2, upstream of ERK1/2 which V1RD11 may modulate, thus impeding cell growth and differentiation signals. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
MEK1/2 inhibitor that can reduce V1RD11 signaling by preventing the activation of ERK1/2, potentially involved in V1RD11-mediated pathways influencing cell proliferation. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Calcium chelator that can inhibit V1RD11 by sequestering intracellular calcium ions, which may play a role in V1RD11's signaling processes, thereby affecting its activity. | ||||||
WZ 4002 | 1213269-23-8 | sc-364655 sc-364655A | 10 mg 50 mg | $180.00 $744.00 | 1 | |
EGFR inhibitor that potentially inhibits V1RD11 by blocking EGFR signaling which V1RD11 might be involved in, leading to reduced cell proliferation and survival signals. | ||||||
GW 5074 | 220904-83-6 | sc-200639 sc-200639A | 5 mg 25 mg | $106.00 $417.00 | 10 | |
RAF inhibitor that can impede V1RD11 function by inhibiting RAF kinases, possibly affecting downstream signaling pathways that V1RD11 could modulate. | ||||||