V1RB3 Inhibitors
V1RB3 inhibitors are a distinct class of chemical compounds specifically designed to modulate the activity of the V1RB3 protein. These inhibitors are characterized by their unique chemical structures, which are crafted to interact selectively with the V1RB3 protein. Typically, the core structure of V1RB3 inhibitors incorporates complex ring systems, heterocyclic compounds, and various functional groups that facilitate binding to the target protein. The design of these inhibitors often involves an intricate balance between hydrophobic and hydrophilic interactions, enabling them to fit precisely into the protein's binding site or alter its conformation.
The development of V1RB3 inhibitors relies on sophisticated synthetic methodologies to produce molecules with high specificity and potency. Chemists employ a range of organic reactions and modifications to create compounds that can effectively bind to V1RB3 and modulate its function. Techniques such as structure-activity relationship (SAR) studies, molecular docking, and computational modeling play crucial roles in optimizing these inhibitors. By understanding the three-dimensional structure of V1RB3 and its interaction with various chemical entities, researchers are able to design and refine inhibitors that offer targeted modulation. This process is iterative, often involving the synthesis of numerous variants and the evaluation of their binding affinity and efficacy through detailed assays and analyses.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by intercalating into DNA, thereby preventing transcription initiation and elongation, ultimately blocking mRNA synthesis and reducing protein expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
α-Amanitin inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by binding to RNA polymerase II, blocking transcriptional elongation, and leading to decreased mRNA levels, consequently reducing the synthesis of the pseudogene protein. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by binding to the 60S ribosomal subunit, preventing peptide bond formation during translation, resulting in decreased synthesis of the pseudogene protein. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by binding to bacterial RNA polymerase, blocking transcription initiation, and indirectly reducing mRNA levels, ultimately leading to decreased pseudogene protein synthesis. | ||||||
Thiolutin | 87-11-6 | sc-200387 sc-200387A | 1 mg 5 mg | $101.00 $406.00 | 1 | |
Thiolutin inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by binding to RNA polymerase and preventing transcriptional elongation, resulting in decreased mRNA synthesis and ultimately reduced protein expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Cordycepin inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by being incorporated into mRNA during transcription, causing premature termination of transcription and reduced mRNA levels, ultimately leading to decreased protein synthesis. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $42.00 $214.00 $832.00 $66.00 | 394 | |
Puromycin inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by incorporating into growing polypeptide chains during translation, causing premature termination of protein synthesis and synthesis of truncated proteins. | ||||||
Siomycin A | 12656-09-6 | sc-202339 sc-202339-CW sc-202339A sc-202339B | 500 µg 500 µg 2.5 mg 25 mg | $450.00 $500.00 $1350.00 $10404.00 | 4 | |
Siomycin A inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by binding to RNA polymerase and preventing the formation of the transcription complex, leading to transcriptional arrest and reduced mRNA synthesis, ultimately decreasing pseudogene protein levels. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $52.00 $125.00 $182.00 | 11 | |
Homoharringtonine inhibits the expression of vomeronasal 1 receptor, pseudogene 28 by binding to the ribosome and inhibiting protein synthesis, resulting in decreased levels of the pseudogene protein. | ||||||