Date published: 2026-5-30

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UQCRH Activators

UQCRH Activators represent a specific category of chemical compounds that have garnered interest in the field of molecular biology and biochemistry. These activators are designed to modulate the activity of the UQCRH gene, with UQCRH referring to Ubiquinol-Cytochrome c Reductase Core Protein H. This gene encodes a protein that plays a crucial role in the mitochondrial respiratory chain, particularly within Complex III, also known as cytochrome bc1 complex. Complex III is a vital component of the electron transport chain, which is responsible for generating adenosine triphosphate (ATP), the cell's primary source of energy. UQCRH Activators constitute a group of molecules engineered to enhance or stimulate the expression and function of the UQCRH gene, ultimately leading to increased activity of the associated protein.

The mechanism by which UQCRH Activators exert their effects typically involves their interaction with specific regulatory elements within the UQCRH gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the UQCRH protein. The UQCRH protein is a critical component of Complex III, where it contributes to electron transfer reactions involved in ATP production. As researchers continue to investigate the functions and potential implications of UQCRH activation, the development and refinement of UQCRH Activators hold promise for advancing our understanding of mitochondrial bioenergetics, cellular respiration, and the broader implications of UQCRH in cellular metabolism and energy production, potentially uncovering novel aspects of mitochondrial function and biochemistry.

SEE ALSO...

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

As an AMPK activator, metformin may enhance mitochondrial biogenesis and potentially upregulate UQCRH as part of improving mitochondrial efficiency.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol can activate SIRT1, leading to improved mitochondrial function and possibly increased expression of components like UQCRH in response to enhanced energy demand.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

As a PPARγ agonist, pioglitazone might stimulate mitochondrial biogenesis, potentially upregulating UQCRH in tissues sensitive to insulin signaling.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

AICAR activates AMPK, which can lead to enhanced mitochondrial biogenesis and possibly increased UQCRH expression in response to cellular energy stress.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$34.00
$74.00
$270.00
$114.00
34
(1)

NAC, as an antioxidant, may reduce oxidative stress, potentially leading to the upregulation of UQCRH to maintain mitochondrial function.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin's antioxidative properties might protect mitochondrial integrity, possibly inducing UQCRH expression as part of a cellular defense mechanism against oxidative damage.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$69.00
$122.00
$212.00
$380.00
$716.00
3
(1)

As an antioxidant and a cofactor in mitochondrial energy metabolism, alpha-lipoic acid might enhance UQCRH expression to support mitochondrial function.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG's effects on cellular metabolism and antioxidative defense might indirectly stimulate UQCRH expression as part of enhancing mitochondrial efficiency.

Coenzyme Q10

303-98-0sc-205262
sc-205262A
1 g
5 g
$71.00
$184.00
1
(1)

As a key component in the electron transport chain, supplementation with Coenzyme Q10 might upregulate UQCRH to optimize mitochondrial electron transport.

Spermidine

124-20-9sc-215900
sc-215900B
sc-215900A
1 g
25 g
5 g
$57.00
$607.00
$176.00
(2)

Spermidine can induce autophagy and mitochondrial renewal, potentially leading to increased expression of mitochondrial components like UQCRH.