UPIIIa Inhibitors
UPIIIa inhibitors are a class of chemical compounds that primarily target and interact with the protein known as Uroplakin IIIa (UPIIIa). UPIIIa is a crucial component of urothelial cells, which line the urinary tract, and plays a vital role in maintaining the structural integrity and functionality of these cells. UPIIIa inhibitors are designed to modulate the activity of this specific protein, making them a subject of interest in the field of urology and related research areas.
These inhibitors typically function by binding to UPIIIa, altering its conformation or activity, and thereby affecting the normal functioning of urothelial cells. While the exact mechanisms of UPIIIa inhibition can vary among different compounds within this class, the overarching goal is to manipulate UPIIIa in a way that can have potential implications in the context of urothelial health. Understanding the structure and function of UPIIIa inhibitors is crucial for researchers and scientists aiming to gain insights into the intricate biology of the urinary tract.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Isoflavone compound that can inhibit tyrosine kinases, which may affect signaling pathways related to cell adhesion and integrity, thus indirectly affecting UPIIIa function. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
Src family kinase inhibitor that can disrupt signaling pathways involved in cytoskeletal organization and might impact the cellular distribution of UPIIIa. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that can lead to similar effects as LY294002, potentially altering UPIIIa dynamics. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor that can interfere with the MAPK/ERK pathway, which may regulate processes affecting UPIIIa. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Also a MEK inhibitor, U0126 can modulate the MAPK/ERK pathway, and consequently affect UPIIIa's role in the urothelium. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that might alter stress response pathways, potentially influencing UPIIIa function. | ||||||
SB 202190 | 152121-30-7 | sc-202334 sc-202334A sc-202334B | 1 mg 5 mg 25 mg | $31.00 $128.00 $454.00 | 45 | |
A selective inhibitor of Gs-alpha subunit of G proteins, which might influence signaling pathways impacting UPIIIa. | ||||||
Gö 6976 | 136194-77-9 | sc-221684 | 500 µg | $227.00 | 8 | |
A potent inhibitor of conventional calcium-dependent protein kinases, which could affect pathways regulating UPIIIa. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor that can disrupt actin cytoskeleton dynamics, potentially influencing the membrane localization of UPIIIa. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Casein kinase 1 inhibitor that might affect the phosphorylation status of proteins involved in the pathways regulating UPIIIa. | ||||||