TXNDC13 inhibitors, as listed above, predominantly focus on modulating the thioredoxin system, given that TXNDC13 belongs to the thioredoxin protein family. Auranofin, PX-12, and Curcumin, by targeting thioredoxin reductase, act as potent disruptors of the thioredoxin system. By inhibiting or modifying the primary enzymes involved in the redox regulation, these agents can impact the function or stability of TXNDC13.
Environmental toxins, such as Cadmium, Arsenic trioxide, and Lead, introduce cellular oxidative stress which exerts pressure on redox balancing systems, including the thioredoxin system. The effect of these toxins can influence the behavior or activity of TXNDC13. Moreover, agents like Cisplatin, Menadione, and Doxorubicin, which have known roles in creating an imbalance in cellular redox systems, can indirectly impact the thioredoxin-related proteins. The other chemicals, including Ebselen, Parthenolide, and Silver nanoparticles, by virtue of their interactions with the thioredoxin system, can provide a avenue for influencing TXNDC13 function.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Auranofin | 34031-32-8 | sc-202476 sc-202476A sc-202476B | 25 mg 100 mg 2 g | $150.00 $210.00 $1899.00 | 39 | |
An inhibitor of thioredoxin reductase, can disrupt the thioredoxin system, potentially influencing TXNDC13 function. | ||||||
PX 12 | 141400-58-0 | sc-358518 sc-358518A | 10 mg 50 mg | $130.00 $495.00 | 9 | |
Inhibits thioredoxin-1, can disrupt the thioredoxin system thereby affecting TXNDC13's function indirectly. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Known to inhibit thioredoxin reductase, can influence the thioredoxin system, which may impact TXNDC13. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
Induces oxidative stress, potentially affecting the thioredoxin system and, in turn, TXNDC13. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Introduces cellular oxidative stress which may influence the thioredoxin system, potentially impacting TXNDC13. | ||||||
Ebselen | 60940-34-3 | sc-200740B sc-200740 sc-200740A | 1 mg 25 mg 100 mg | $32.00 $133.00 $449.00 | 5 | |
Thioredoxin reductase modulator, can influence the thioredoxin system and thereby affect TXNDC13. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $79.00 $300.00 | 32 | |
Disrupts the thioredoxin system by binding to thioredoxin reductase, which can indirectly influence TXNDC13. | ||||||
Vitamin K3 | 58-27-5 | sc-205990B sc-205990 sc-205990A sc-205990C sc-205990D | 5 g 10 g 25 g 100 g 500 g | $25.00 $35.00 $46.00 $133.00 $446.00 | 3 | |
Generate oxidative stress, potentially disrupting the thioredoxin system and influencing TXNDC13. | ||||||
Lead | 7439-92-1 | sc-250236 | 2 kg | $102.00 | ||
Can induce oxidative stress, potentially impacting the thioredoxin system and TXNDC13. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Known to cause cellular oxidative stress, can influence the thioredoxin system, which may indirectly impact TXNDC13. | ||||||