TTC4 Activators
TTC4 activators include compounds that influence various aspects of cellular regulation, particularly focusing on protein interaction networks and stress response mechanisms. In the first paragraph, the focus is on chemicals like Geldanamycin and 17-AAG, which inhibit Hsp90, a chaperone involved in protein folding.MG132might lead to an increased need for TTC4's function in protein quality control due to the accumulation of misfolded proteins.
The emphasis is on compounds like Curcumin, Resveratrol, and Rapamycin, which modulate various signaling pathways including those related to cellular stress, aging, and mTOR signaling. These could indirectly enhance TTC4's activity in related processes. Lithium Chloride, SB203580, and SP600125, affecting GSK-3, p38 MAPK, and JNK signaling respectively, might also enhance TTC4's role in stress response and other regulatory pathways. U0126 and Bortezomib provide further for TTC4 activation by modulating MAPK/ERK signaling and proteasome activity. Lastly, Sodium Butyrate, by affecting histone deacetylation, might indirectly enhance TTC4 activity through changes in gene expression patterns.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
A Hsp90 inhibitor, could indirectly enhance TTC4 activity by affecting protein folding and stability processes. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $66.00 $153.00 | 16 | |
Another Hsp90 inhibitor, potentially enhancing TTC4 function through altered chaperone-mediated protein stabilization. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor, could lead to accumulation of misfolded proteins, indirectly enhancing TTC4 activity in protein quality control. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates various signaling pathways; could enhance TTC4 activity in cellular stress response and protein interaction networks. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Influences sirtuin pathways; might enhance TTC4 activity in processes related to cellular stress response and aging. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences Glycogen Synthase Kinase 3 (GSK-3) signaling, potentially enhancing TTC4 activity in Wnt signaling pathways. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Proteasome inhibitor, could enhance TTC4 activity by affecting protein degradation pathways. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Histone deacetylase inhibitor, might influence gene expression in a way that indirectly enhances TTC4 activity. | ||||||