Date published: 2026-5-30

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TSPYL1 Activators

Forskolin and PGE2 are chemicals that directly target adenylate cyclase and EP receptors to increase cAMP levels, which can then lead to the upregulation of TSPYL1 in cAMP-dependent pathways. EGF works through EGF receptor activation, initiating phosphorylation cascades that can enhance TSPYL1 activity. Ionomycin functions by increasing intracellular calcium levels, subsequently activating calcium-dependent pathways that involve TSPYL1.

Retinoic Acid and 5-Azacytidine affect TSPYL1 activity through mechanisms of gene expression and epigenetic regulation. They interact with nuclear receptors and inhibit DNA methyltransferases, respectively, to upregulate TSPYL1. Quercetin acts on the JNK pathway, influencing phosphorylation events that can result in elevated TSPYL1 levels. Trichostatin A is an HDAC inhibitor that alters the epigenetic landscape, particularly in histone acetylation, to upregulate TSPYL1. L-Ascorbic acid enhances collagen production and can elevate TSPYL1 levels involved in cellular matrix formation. Estradiol and Isoformononetin work through specific pathway targets-estrogen receptors and AMPK, respectively-to trigger downstream effects leading to TSPYL1 activation.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Elevates cAMP levels, which can upregulate TSPYL1 through cAMP-dependent pathways.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

Raises intracellular calcium levels, triggering pathways that can upregulate TSPYL1.

PGE2

363-24-6sc-201225
sc-201225C
sc-201225A
sc-201225B
1 mg
5 mg
10 mg
50 mg
$57.00
$159.00
$275.00
$678.00
37
(1)

Activates EP receptors and increases cAMP, which can result in TSPYL1 upregulation.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Upregulates TSPYL1 through nuclear receptors, impacting gene expression.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

DNA methyltransferase inhibitor that upregulates TSPYL1 through epigenetic control.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Activates the JNK pathway, resulting in increased TSPYL1 activity.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

HDAC inhibitor that upregulates TSPYL1 through histone acetylation.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$46.00
5
(1)

Enhances collagen production, potentially leading to increased TSPYL1 levels that may be involved in cellular matrix formation.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

Activates estrogen receptors, triggering pathways that lead to elevated TSPYL1 activity.