TSGA10 inhibitors, collectively referred to as a chemical class, are a group of small molecules designed to target and modulate the activity of the Testis Specific Gene Antigen 10 (TSGA10) protein. TSGA10 is a protein that plays a crucial role in various cellular processes, particularly in the context of cancer and cell cycle regulation. Inhibitors within this class are primarily developed to investigate the molecular interactions and functions of TSGA10 within cells, providing valuable insights into its role and as a target.
These inhibitors are meticulously designed to interfere with the interactions between TSGA10 and its binding partners, often focusing on key protein-protein interactions. For example, some TSGA10 inhibitors may disrupt its association with the tumor suppressor protein p53 or with other regulatory molecules, leading to downstream effects on cellular processes. The mechanism of action typically involves binding to specific regions of TSGA10 or its interacting partners, thereby altering their physical interactions. By modulating TSGA10's function through these small molecules, researchers can gain a deeper understanding of the protein's role in cancer progression, cell cycle regulation, and other cellular processes.In summary, TSGA10 inhibitors are a class of chemical compounds designed for research purposes to probe the molecular mechanisms involving TSGA10 within cells.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(+)-Nutlin-3 | 675576-97-3 | sc-222085 sc-222085A | 500 µg 1 mg | $94.00 $122.00 | ||
Nutlin-3 inhibits TSGA10 by disrupting the interaction between TSGA10 and p53, promoting p53 stabilization and activation, leading to cell cycle arrest and apoptosis in cancer cells. | ||||||
Pifithrin-α hydrobromide | 63208-82-2 | sc-45050 sc-45050A | 5 mg 25 mg | $120.00 $300.00 | 36 | |
Pifithrin-α(HBr) inhibits TSGA10 by preventing the binding of TSGA10 to p53, thus enhancing p53's transcriptional activity and promoting apoptosis in cancer cells. | ||||||
PRIMA-1 | 5608-24-2 | sc-200927 sc-200927A | 5 mg 25 mg | $102.00 $408.00 | 1 | |
PRIMA-1 restores the transcriptional activity of mutant p53, indirectly affecting TSGA10 by promoting p53-mediated cell cycle arrest and apoptosis. | ||||||
p53 Activator III, RITA | 213261-59-7 | sc-202753 sc-202753A sc-202753B sc-202753C | 1 mg 10 mg 100 mg 500 mg | $112.00 $273.00 $1564.00 $5205.00 | 9 | |
RITA induces p53-dependent apoptosis by disrupting the TSGA10-p53 interaction and stabilizing p53, leading to cell cycle arrest and cell death. | ||||||
NSC 319726 | 71555-25-4 | sc-477736 | 10 mg | $159.00 | ||
NSC319726 inhibits TSGA10 by interfering with its interaction with p53, leading to increased p53 activity and apoptosis in cancer cells. | ||||||
CP 31398 dihydrochloride | 259199-65-0 | sc-205270 sc-205270A | 10 mg 50 mg | $109.00 $434.00 | ||
CP-31398 enhances p53 activity by disrupting TSGA10-p53 binding, promoting p53-dependent apoptosis and cell cycle arrest in cancer cells. | ||||||
Tenovin-6 | 1011557-82-6 | sc-224296 sc-224296A | 1 mg 5 mg | $272.00 $1214.00 | 9 | |
Tenovin-6 targets TSGA10 and MDM2, stabilizing p53 and promoting its transcriptional activity, leading to cell cycle arrest and apoptosis. | ||||||
PRIMA-1MET | 5291-32-7 | sc-361295 sc-361295A | 10 mg 25 mg | $153.00 $325.00 | 5 | |
PRIMA-1Met restores mutant p53 function, indirectly affecting TSGA10 by promoting p53-mediated cell cycle arrest and apoptosis. | ||||||
Pifithrin-μ | 64984-31-2 | sc-203195 sc-203195A | 10 mg 50 mg | $130.00 $379.00 | 4 | |
Pifithrin-μ disrupts the TSGA10-p53 interaction, enhancing p53's transcriptional activity and promoting apoptosis in cancer cells. | ||||||