TRIM73 Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD 98059 is an inhibitor of mitogen-activated protein kinase kinase (MEK), which by inhibiting this kinase, decreases the activity of the MAPK/ERK pathway. Since TRIM73 is a protein that could be regulated by this pathway, use of PD 98059 could lead to a reduction in TRIM73 activity as the downstream signaling is inhibited. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a potent inhibitor of phosphoinositide 3-kinases (PI3K). Inhibition of PI3K signaling can lead to decreased Akt phosphorylation and activity. As Akt signaling could be involved in the regulation of TRIM73, the inhibition of this pathway by LY294002 would result in the indirect decrease of TRIM73 activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAP kinase. The p38 MAPK pathway is known for its role in stress responses, and if TRIM73 activity is modulated as part of this response, the inhibition of p38 MAPK by SB203580 could reduce TRIM73 function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK). JNK is involved in regulatory processes including apoptosis and cellular differentiation. If TRIM73 is implicated in these JNK-mediated processes, inhibition by SP600125 could result in decreased TRIM73 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is an inhibitor of MEK1/2, leading to suppression of the MAPK/ERK signaling pathway. If TRIM73 function is dependent on this signaling pathway, inhibition by U0126 could lead to reduced TRIM73 activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent inhibitor of PI3K. By inhibiting PI3K, it disrupts the PI3K/Akt pathway, which can regulate various proteins involved in cellular survival and growth. If TRIM73 is regulated through this pathway, its activity would be indirectly decreased by Wortmannin. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor and thus interferes with the mTOR signaling pathway, which is central to cell growth and metabolism. If the mTOR pathway has regulatory effects on TRIM73, then Rapamycin could lead to a reduction in its activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a ROCK (Rho-associated protein kinase) inhibitor. ROCK is involved in cytoskeletal organization and cellular contraction. If TRIM73 has a functional role related to these cellular processes, inhibition by Y-27632 could decrease TRIM73 activity. | ||||||
SL-327 | 305350-87-2 | sc-200685 sc-200685A | 1 mg 10 mg | $107.00 $332.00 | 7 | |
SL327 is an inhibitor of MEK1/2, which suppresses the MAPK/ERK pathway. If the regulation of TRIM73 is connected to this pathway, then inhibition by SL327 could diminish TRIM73 function. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
Gö 6983 is a broad-spectrum protein kinase C (PKC) inhibitor. If TRIM73 activity is modulated by PKC-mediated signaling, inhibition by Gö 6983 would lead to decreased TRIM73 activity. | ||||||