Date published: 2025-12-9

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TRIM36 Activators

TRIM36 activators represent a class of chemical compounds that have garnered significant attention in the field of molecular biology and cellular research due to their ability to modulate the activity of TRIM36, a key protein in various cellular processes. TRIM36, short for Tripartite Motif Containing 36, is a member of the TRIM protein family, which plays a crucial role in regulating a wide range of cellular functions, including immunity, antiviral responses, and cell differentiation. TRIM36 itself is a multifunctional E3 ubiquitin ligase, meaning it is involved in tagging specific proteins for degradation via the ubiquitin-proteasome system, which is essential for maintaining cellular homeostasis.

The development of TRIM36 activators provides researchers with a powerful tool to modulate the function of this protein. By binding to TRIM36 and altering its activity, these chemical compounds enable scientists to investigate the downstream effects on various cellular pathways, helping to unravel the intricate mechanisms through which TRIM36 influences cellular processes. These activators can be employed to gain insights into the molecular underpinnings of the immune response, viral defense mechanisms, and other critical aspects of cellular biology. Moreover, they may prove instrumental in deciphering the functional significance of TRIM36 in normal cellular function and disease, offering a deeper understanding of the intricate network of protein interactions and pathways that govern our biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA indirectly increases TRIM36 activation by activating the NF-κB pathway, a regulator of immune and inflammatory responses.

Polyinosinic acid - polycytidylic acid sodium salt, double-stranded

42424-50-0sc-204854
sc-204854A
10 mg
100 mg
$139.00
$650.00
2
(1)

Poly(I:C) activates innate immune responses and indirectly activates TRIM36 as part of the immune defense against viral infections.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Anisomycin indirectly activates TRIM36 through cellular responses to stress and inflammation by activating the p38 MAPK pathway.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

TSA indirectly activates TRIM36 by affecting epigenetic regulation of gene expression as a histone deacetylase inhibitor.

Epoxomicin

134381-21-8sc-201298C
sc-201298
sc-201298A
sc-201298B
50 µg
100 µg
250 µg
500 µg
$134.00
$215.00
$440.00
$496.00
19
(2)

Epoxomicin indirectly activates TRIM36 by affecting protein degradation pathways, potentially stabilizing TRIM36 or its substrates.