Triadin Inhibitors
Triadin inhibitors belong to a specific chemical class of compounds that have been designed and studied to selectively target and inhibit the function of triadin, a protein predominantly found in the sarcoplasmic reticulum of muscle cells. Triadin plays a crucial role in regulating calcium release during muscle contraction by interacting with the ryanodine receptor (RyR), a calcium channel responsible for releasing calcium ions from the sarcoplasmic reticulum into the cytoplasm. Inhibition of triadin aims to disrupt its interaction with RyR, modulating calcium release dynamics.
The chemical structures of triadin inhibitors can vary, with some being peptides found in triadin itself or other interacting proteins, while others might be small-molecule compounds. These inhibitors are designed to interfere with the triadin-RyR complex, altering calcium handling in muscle cells. The research and development of triadin inhibitors contribute to a deeper understanding of the calcium signaling processes in muscle physiology. Continued investigation in this chemical class may shed light on the intricate regulation of calcium dynamics and its implications in muscle function.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tetracaine | 94-24-6 | sc-255645 sc-255645A sc-255645B sc-255645C sc-255645D sc-255645E | 5 g 25 g 100 g 500 g 1 kg 5 kg | $66.00 $309.00 $500.00 $1000.00 $1503.00 $5000.00 | ||
Local anesthetic that can inhibit calcium release from the sarcoplasmic reticulum, potentially reducing Triadin activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
A SERCA pump inhibitor, disrupting calcium storage and potentially affecting Triadin's role in calcium release. | ||||||
Diltiazem | 42399-41-7 | sc-204726 sc-204726A | 1 g 5 g | $209.00 $464.00 | 4 | |
Calcium channel blocker, altering calcium influx and potentially impacting Triadin's function in excitation-contraction coupling. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
Influences intracellular calcium release channels, potentially affecting Triadin's role in calcium signaling. | ||||||
Procaine | 59-46-1 | sc-296134 sc-296134A sc-296134B sc-296134C | 25 g 50 g 500 g 1 kg | $108.00 $189.00 $399.00 $616.00 | 1 | |
Local anesthetic that can inhibit calcium release, potentially reducing the activity of Triadin. | ||||||
Gadolinium(III) chloride | 10138-52-0 | sc-224004 sc-224004A | 5 g 25 g | $150.00 $350.00 | 4 | |
A blocker of certain calcium channels, could impact Triadin's role in excitation-contraction coupling. | ||||||
SK&F 96365 | 130495-35-1 | sc-201475 sc-201475B sc-201475A sc-201475C | 5 mg 10 mg 25 mg 50 mg | $101.00 $155.00 $389.00 $643.00 | 2 | |
Inhibits receptor-operated calcium channels, potentially affecting Triadin's function in calcium signaling. | ||||||
Carvedilol | 72956-09-3 | sc-200157 sc-200157A sc-200157B sc-200157C sc-200157D | 100 mg 1 g 10 g 25 g 100 g | $122.00 $235.00 $520.00 $979.00 $1500.00 | 2 | |
A beta-blocker that can influence calcium dynamics, potentially impacting Triadin's activity. | ||||||
Nicardipine hydrochloride | 54527-84-3 | sc-202731 sc-202731A | 1 g 5 g | $32.00 $81.00 | 5 | |
Calcium channel blocker, could alter Triadin's function in muscle cells by modifying calcium signaling. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
Another calcium channel blocker, it can alter calcium dynamics in muscle cells, indirectly influencing Triadin. | ||||||