TMPRSS2 Activators
TMPRSS2, or transmembrane protease serine 2, is a protein that has gained considerable attention due to its role in physiological processes and in the life cycle of some viruses. The protein's primary function is to cleave and activate certain proteins, facilitating their subsequent activity in the body. An important distinction in studying TMPRSS2 is the delineation between its natural inducers and chemical activators. While some molecules can increase the expression of TMPRSS2, activators directly augment the enzyme's activity without necessarily altering its levels.
TMPRSS2 activators belong to a class of compounds that can boost the proteolytic action of TMPRSS2. These activators work by interacting with the protein's active site or its allosteric sites, essentially modulating the protein's conformation and making it more receptive to its substrates. The precise mechanism of action of these activators can vary, and in some cases, remains to be fully elucidated. Their interaction with TMPRSS2 can be influenced by factors like the local pH, presence of other interacting molecules, and the specific physiological environment. Research into TMPRSS2 activators has burgeoned, driven by the need to understand the intricate interplay of proteins in cellular processes and the fundamental biochemistry that underpins these interactions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a glucocorticoid that can potentially influence the expression of a variety of genes. Some studies have indicated its ability to upregulate TMPRSS2 expression. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $81.00 $306.00 | 32 | |
Parthenolide, a sesquiterpene lactone from the feverfew plant, has been investigated for its influence on gene expression. It might modulate TMPRSS2 levels, but the exact mechanism remains unclear. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a compound found in turmeric, has the potential to affect various signaling pathways. Its interaction with TMPRSS2 expression has been a subject of research, with some studies suggesting an induction. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a polyphenolic compound present in grapes. Its broad range of effects on cellular processes includes potential modulation of TMPRSS2, although the exact mechanisms are still under investigation. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $105.00 $214.00 $6255.00 | 2 | |
Emodin, a compound present in rhubarb, may influence TMPRSS2 expression, possibly through its interaction with cellular signaling pathways. Its precise role remains a subject of research. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a soy isoflavone, can modulate several cellular processes. There's evidence suggesting it might influence TMPRSS2 expression, but the precise mechanisms are not fully elucidated. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid found in many plants, may influence various gene expression profiles. Its potential induction of TMPRSS2 has been studied, although the exact mechanism is still being explored. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Kaempferol, another flavonoid, has been researched for its influence on cellular processes. Its potential effect on TMPRSS2 expression is an area of scientific interest. | ||||||
Ursolic Acid | 77-52-1 | sc-200383 sc-200383A | 50 mg 250 mg | $56.00 $180.00 | 8 | |
Ursolic acid, found in apple peels, may modulate various gene expressions. Its potential role in influencing TMPRSS2 has been a topic of scientific investigation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, a compound in cruciferous vegetables, has various effects on cellular processes. Some studies suggest it might modulate TMPRSS2 expression, though the mechanisms remain to be fully elucidated. | ||||||