TMEM64, or Transmembrane Protein 64, is a protein encoded by the TMEM64 gene in humans. As a member of the transmembrane protein family, TMEM64 is embedded within the lipid bilayer of cells and is presumed to perform specific functions that are essential to cellular homeostasis and physiology.Although the comprehensive functional profile of TMEM64 has not been fully elucidated, proteins of this nature typically engage in significant biological activities. They may act as channels or transporters that control the flow of ions, metabolites, and other small molecules across the cellular membrane. TMEM64 could, therefore, be involved in maintaining the ionic balance and homeostasis within cells, which is vital for numerous cellular processes including signaling, volume regulation, and substance exchange.
Transmembrane proteins like TMEM64 are also often key players in signal transduction pathways. They can serve as receptors that recognize and bind specific ligands, triggering intracellular signaling cascades that lead to various cellular responses such as growth, differentiation, migration, and apoptosis. TMEM64 may thus participate in the complex network of signaling that dictates cell fate and behavior.Additionally, TMEM64's transmembrane nature suggests a potential role in cell-cell or cell-matrix interactions, contributing to the structural integrity of tissues and the coordination of multicellular functions. These interactions can be critical for tissue development, remodeling, and repair.In-depth research into TMEM64's structure and activity is necessary to accurately define its role within cells and tissues. Understanding TMEM64's function could have important implications for identifying its involvement in pathophysiological conditions, especially those related to membrane transport and signaling disorders. As research progresses, TMEM64 may emerge as a significant protein with potential as a target or a biomarker for specific diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
An ionophore that disrupts intracellular transport and Golgi function, potentially affecting TMEM64 by altering intracellular trafficking and membrane dynamics. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Inhibits protein transport from the endoplasmic reticulum to the Golgi apparatus, potentially influencing TMEM64 involved in intracellular trafficking. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Microtubule depolymerizing agent, could influence TMEM64 activity by affecting cytoskeletal dynamics and membrane trafficking. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Inhibitor of actin polymerization, potentially affecting TMEM64 by altering cytoskeletal organization and related membrane dynamics. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynamin inhibitor, might affect TMEM64 by impacting endocytic processes and vesicular trafficking. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $191.00 $683.00 | 11 | |
Specific disruptor of the Golgi apparatus, potentially influencing TMEM64 function related to Golgi and intracellular trafficking. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC), potentially modulating TMEM64 activity through PKC-mediated signaling pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, which could influence TMEM64 activity through cAMP-dependent signaling pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3K inhibitor, potentially affecting TMEM64 by modulating the PI3K/Akt signaling pathway involved in various cellular processes including membrane trafficking. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Blocks clathrin-mediated endocytosis, potentially affecting TMEM64's role in cellular trafficking processes. | ||||||