TMEM245 activators, as hypothesized in this context, represent a diverse group of chemical compounds that indirectly influence the activity or expression of the TMEM245 protein through a variety of mechanisms. These activators target different aspects of cellular function, from the modulation of cAMP levels and activation of specific receptors that influence gene expression, to the alteration of cellular stress responses and metabolic signaling pathways. This indirect activation approach recognizes the complex regulation of transmembrane proteins and leverages the interconnected nature of cellular signaling pathways to influence the expression or function of TMEM245.
For instance, compounds like forskolin and resveratrol act by elevating intracellular signaling molecules or activating specific sirtuins, respectively, which can lead to changes in the cellular environment conducive to the expression or activity of TMEM245. Similarly, agents such as vitamin D3 and retinoic acid work through their respective receptors to directly modulate gene expression, potentially leading to an increase in TMEM245 levels. The role of dietary components and supplements, such as omega-3 fatty acids and zinc, underscores the potential for nutritional and environmental factors to influence gene expression and protein activity within the cell.
This speculative list illustrates the potential avenues through which the activity or expression of TMEM245 might be enhanced, reflecting a nuanced understanding of cellular biology and the multifaceted roles that proteins play within complex cellular networks. By focusing on the broader cellular context and the myriad ways in which chemical compounds can influence gene expression and signaling pathways, this approach highlights the potential for targeting upstream regulatory mechanisms or related cellular processes to modulate the function of proteins like TMEM245 indirectly.
VEJA TAMBÉM
Items 1 to 10 of 12 total
Mostrar:
Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Aumenta os níveis de AMPc, aumentando potencialmente a expressão do TMEM245 através de vias dependentes de AMPc. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influencia a expressão genética através dos receptores de ácido retinóico, potencialmente suprarregulando o TMEM245. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Modula as vias de sinalização, possivelmente aumentando a expressão do TMEM245 ao afetar a regulação dos genes. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Afecta a sinalização NF-κB, conduzindo potencialmente à modulação da expressão de TMEM245. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Ativa a SIRT1, influenciando as vias que podem aumentar a expressão do TMEM245 em resposta ao stress celular. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Ativa o recetor da vitamina D, afectando potencialmente a expressão do TMEM245 através da regulação genómica. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Induz a sinalização NRF2, possivelmente aumentando a expressão de TMEM245 através da modulação da resposta ao stress oxidativo. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Ativa a AMPK, influenciando potencialmente as vias de sinalização metabólica que regulam positivamente o TMEM245. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Um inibidor da histona desacetilase que pode aumentar a expressão do TMEM245 através da alteração da acessibilidade da cromatina. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Essencial para a síntese de ADN e para a regulação da transcrição, aumentando potencialmente a expressão de TMEM245. |