Date published: 2026-4-1

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TMEM191C Inhibitors

Transmembrane Protein 191C (TMEM191C) is a protein encoded by the TMEM191C gene in humans. As the name suggests, TMEM191C is a transmembrane protein, meaning that it spans the entire lipid bilayer of the cell membrane. This structural characteristic suggests that TMEM191C has a role in either cell signaling, ion transport, or the maintenance of cell structure and intercellular communication.

However, proteins within the TMEM family often play roles in various cellular processes, including the transport of molecules across cellular membranes, participating in the endoplasmic reticulum's (ER) protein-folding machinery, or acting as receptors in signal transduction pathways.Transmembrane proteins are critical for cells as they can mediate interactions between the cell's internal and external environments. They are often involved in the transfer of ions or signaling molecules, as well as in the adhesion between cells and the extracellular matrix. Given its transmembrane nature, TMEM191C may be involved in one or several of these processes, contributing to the cell's physiological functions.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Nifedipine

21829-25-4sc-3589
sc-3589A
1 g
5 g
$59.00
$173.00
15
(1)

Nifedipine might indirectly affect TMEM191C by modulating calcium signaling, which can be relevant for the function of many transmembrane proteins.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin, a PI3K/Akt/mTOR inhibitor, could influence TMEM191C indirectly through cellular signaling pathways associated with membrane dynamics and protein trafficking.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A may indirectly affect TMEM191C through its role in gene expression and chromatin remodeling.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Bortezomib may influence TMEM191C indirectly by modulating protein degradation pathways, potentially affecting transmembrane protein turnover.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

BAY 11-7082, an NF-κB pathway inhibitor, could indirectly impact TMEM191C by affecting cellular signaling involved in inflammation and stress responses.

Ruxolitinib

941678-49-5sc-364729
sc-364729A
sc-364729A-CW
5 mg
25 mg
25 mg
$251.00
$500.00
$547.00
16
(1)

Ruxolitinib might indirectly impact TMEM191C by modulating JAK/STAT signaling pathways.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Chloroquine, an autophagy modulator, could have indirect implications for TMEM191C through its role in cellular degradation processes.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

U0126, an inhibitor of the ERK/MAPK pathway, might indirectly affect TMEM191C by influencing cell differentiation and growth pathways.

17-AAG

75747-14-7sc-200641
sc-200641A
1 mg
5 mg
$67.00
$156.00
16
(2)

17-AAG, an HSP90 inhibitor, could affect TMEM191C indirectly by impacting protein folding and stability.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine might have an indirect effect on TMEM191C by altering gene expression patterns via DNA methylation changes.