TMEM191B, or Transmembrane Protein 191B, is a protein that in humans is encoded by the TMEM191B gene. TMEM191B belongs to a large family of transmembrane proteins, which are characterized by their ability to span the lipid bilayer of cell membranes one or more times. These proteins play diverse roles in cellular physiology, ranging from transport of molecules across the membrane to signal transduction and acting as cell surface receptors.The specific functions of TMEM191B are not well-characterized within the scientific literature, reflective of the relatively common situation where gene products are identified through genomic sequencing efforts before their roles within the cell are fully understood. However, given its classification as a transmembrane protein, it can be reasonably hypothesized that TMEM191B may be involved in processes requiring membrane localization, such as intracellular signaling, transport of molecules, or maintenance of cellular structure and integrity.
In general, transmembrane proteins like TMEM191B are critical for the proper functioning of cells and tissues. They are involved in the selective permeability of the cellular membrane, allowing cells to maintain a distinct internal environment. They can also serve as conduits for communication between the cell and its external environment, enabling cells to respond to extracellular signals and cues.The expression pattern of TMEM191B, including which tissues or cell types it is predominantly expressed in, remains to be fully detailed. This information, along with functional assays and experiments, will be crucial in building an understanding of the biological relevance of this protein.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
An ionophore that disrupts intracellular transport and Golgi function, potentially affecting TMEM191B by altering intracellular trafficking and membrane dynamics. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Inhibits protein transport from the endoplasmic reticulum to the Golgi apparatus, potentially influencing TMEM191B involved in intracellular trafficking. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Microtubule depolymerizing agent, could influence TMEM191B activity by affecting cytoskeletal dynamics and membrane trafficking. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Inhibitor of actin polymerization, potentially affecting TMEM191B by altering cytoskeletal organization and related membrane dynamics. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
Dynamin inhibitor, might affect TMEM191B by impacting endocytic processes and vesicular trafficking. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $187.00 $670.00 | 11 | |
Specific disruptor of the Golgi apparatus, potentially influencing TMEM191B function related to Golgi and intracellular trafficking. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC), potentially modulating TMEM191B activity through PKC-mediated signaling pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, which could influence TMEM191B activity through cAMP-dependent signaling pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor, potentially affecting TMEM191B by modulating the PI3K/Akt signaling pathway involved in various cellular processes including membrane trafficking. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $60.00 $108.00 | 21 | |
Blocks clathrin-mediated endocytosis, potentially affecting TMEM191B's role in cellular trafficking processes. | ||||||