TMEM119 Activators
TMEM119 is a transmembrane protein that has been identified in microglia, the resident immune cells of the central nervous system. These proteins are integral components of the cell membrane, suggesting their involvement in cellular signaling and communication. In the context of potential activators, it is conceivable that researchers are exploring compounds or molecules that can modulate the function or expression of TMEM119. Activators in the realm of molecular biology typically refer to substances that enhance the activity of a particular protein, either by promoting its expression or by augmenting its functional capabilities.
In the case of TMEM119 activators, these compounds could potentially influence microglial function, playing a role in processes such as immune response or cellular maintenance within the central nervous system. Understanding the intricacies of TMEM119 activation and its implications would likely involve detailed studies at the molecular and cellular levels. Researchers may investigate how these activators influence the behavior of microglia and whether such modulation has any impact on neurological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $663.00 | 2 | |
Toll-like receptor agonist that stimulates immune responses by directly activating Toll-like receptors, possibly activating TMEM119 expression indirectly through immune signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Protein kinase C activator that induces NF-κB activation, activating inflammatory responses and potentially activating TMEM119 expression indirectly through NF-κB signaling. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Thiazolidinedione that modulates immune regulation and inflammatory responses, potentially activating TMEM119 expression indirectly through the activation of PPARγ-dependent pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Adenylyl cyclase activator that modulates cAMP levels, activating immune responses and potentially activating TMEM119 expression indirectly through cAMP-dependent pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Epigenetic modulator that influences histone acetylation and gene expression, potentially activating TMEM119 expression indirectly through epigenetic regulation. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Calcium modulator that influences intracellular calcium levels, activating cellular processes, and potentially activating TMEM119 expression indirectly through calcium-dependent signaling pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
Kinase inhibitor that targets specific protein kinases involved in microglial activation pathways, potentially activating TMEM119 expression indirectly by modulating kinase-dependent signaling cascades. | ||||||