Date published: 2026-2-14

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TIGD2 Activators

The chemical class known as TIGD2 activators encompasses a diverse range of compounds that can influence the activity of the TIGD2 protein through various mechanisms that alter cellular processes and gene expression. These activators are typically categorized based on their ability to modulate epigenetic markers, influence signaling pathways, or affect the cellular environment in a manner that can lead to the activation of TIGD2. Many of these chemicals act as inhibitors or antagonists to enzymes that modify the structure of chromatin, such as DNA methyltransferases or histone deacetylases. By inhibiting these enzymes, these chemicals can alter gene expression patterns, which can lead to increased expression or functional activation of TIGD2.

The breadth of this chemical class reflects the complex interaction between small molecules and cellular machinery. Some members of this group function by directly inhibiting the activity of enzymes that control the epigenetic landscape, effectively loosening the tightly packed chromatin to allow for greater gene expression. Others operate indirectly by stimulating second messenger systems, which then trigger a cascade of intracellular events that can culminate in the activation of TIGD2. These activators can also exert their influence on TIGD2 by modulating the activity of various protein kinases and phosphatases, which play pivotal roles in cellular signaling networks. By doing so, they can impact the phosphorylation status of proteins and transcription factors that are critical for the expression of TIGD2. It is through these intricate biological processes that the activators can exert their influence on the TIGD2 protein, demonstrating their integral role in the dynamic regulation of gene expression.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor; it could affect gene expression regulation by altering methylation patterns, which could activate TIGD2.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

A histone deacetylase inhibitor; it could alter chromatin structure, which could activate regions where TIGD2 might exert its function.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

A metabolite of vitamin A; it can regulate gene expression and development, which could activate the expression of genes like TIGD2 during differentiation.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

A GSK-3 inhibitor; it influences the WNT signaling pathway and could activate the expression of genes regulated by this pathway, including TIGD2.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

An activator of adenylate cyclase, leading to an increase in cAMP, which can modulate various signaling pathways and could activate TIGD2.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

A diacylglycerol analog that activates protein kinase C (PKC); it could modify signaling pathways and could activate TIGD2 regulation.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor; it affects cell growth and proliferation pathways, which could activate the expression of genes like TIGD2.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

A histone deacetylase inhibitor; it has effects on chromatin remodeling and gene expression that could activate TIGD2 function.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

A histone deacetylase inhibitor; it could impact chromatin structure and gene expression, which could activate TIGD2's role in the genome.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A polyphenol found in green tea; it has various effects on cellular signaling and epigenetic regulation, which could activate genes like TIGD2.