The chemical class known as TIGD2 activators encompasses a diverse range of compounds that can influence the activity of the TIGD2 protein through various mechanisms that alter cellular processes and gene expression. These activators are typically categorized based on their ability to modulate epigenetic markers, influence signaling pathways, or affect the cellular environment in a manner that can lead to the activation of TIGD2. Many of these chemicals act as inhibitors or antagonists to enzymes that modify the structure of chromatin, such as DNA methyltransferases or histone deacetylases. By inhibiting these enzymes, these chemicals can alter gene expression patterns, which can lead to increased expression or functional activation of TIGD2.
The breadth of this chemical class reflects the complex interaction between small molecules and cellular machinery. Some members of this group function by directly inhibiting the activity of enzymes that control the epigenetic landscape, effectively loosening the tightly packed chromatin to allow for greater gene expression. Others operate indirectly by stimulating second messenger systems, which then trigger a cascade of intracellular events that can culminate in the activation of TIGD2. These activators can also exert their influence on TIGD2 by modulating the activity of various protein kinases and phosphatases, which play pivotal roles in cellular signaling networks. By doing so, they can impact the phosphorylation status of proteins and transcription factors that are critical for the expression of TIGD2. It is through these intricate biological processes that the activators can exert their influence on the TIGD2 protein, demonstrating their integral role in the dynamic regulation of gene expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor; it could affect gene expression regulation by altering methylation patterns, which could activate TIGD2. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor; it could alter chromatin structure, which could activate regions where TIGD2 might exert its function. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of vitamin A; it can regulate gene expression and development, which could activate the expression of genes like TIGD2 during differentiation. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
A GSK-3 inhibitor; it influences the WNT signaling pathway and could activate the expression of genes regulated by this pathway, including TIGD2. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An activator of adenylate cyclase, leading to an increase in cAMP, which can modulate various signaling pathways and could activate TIGD2. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
A diacylglycerol analog that activates protein kinase C (PKC); it could modify signaling pathways and could activate TIGD2 regulation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor; it affects cell growth and proliferation pathways, which could activate the expression of genes like TIGD2. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A histone deacetylase inhibitor; it has effects on chromatin remodeling and gene expression that could activate TIGD2 function. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
A histone deacetylase inhibitor; it could impact chromatin structure and gene expression, which could activate TIGD2's role in the genome. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol found in green tea; it has various effects on cellular signaling and epigenetic regulation, which could activate genes like TIGD2. | ||||||