THEM92 Inhibitors
TMEM92 inhibitors are compounds that can affect the function or expression of transmembrane proteins indirectly. These chemicals rely on the potential interactions or effects on general transmembrane proteins or cellular membranes. For instance, compounds like Chlorpromazine are known to alter membrane fluidity, which can influence the function or localization of transmembrane proteins like TMEM92.
Similarly, calcium channel blockers such as Verapamil and Nifedipine might indirectly affect TMEM92 by modulating the activity of certain membrane proteins. On the other hand, drugs like Filipin, which disrupt lipid rafts, can affect the microenvironment of transmembrane proteins and thus their functionality. Additionally, ion channel inhibitors, such as Amiloride or DIDS, by modifying ion homeostasis, can potentially influence the function or expression of proteins like TMEM92.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
An antipsychotic known to affect various transmembrane proteins by altering membrane fluidity, potentially affecting TMEM92. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
A calcium channel blocker that can inhibit the function of certain transmembrane proteins. | ||||||
Amiloride • HCl | 2016-88-8 | sc-3578 sc-3578A | 25 mg 100 mg | $22.00 $57.00 | 6 | |
Known to inhibit some transmembrane ion channels, potentially affecting proteins like TMEM92. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
Another calcium channel blocker that could indirectly influence TMEM92 by modulating membrane protein function. | ||||||
Filipin III | 480-49-9 | sc-205323 sc-205323A | 500 µg 1 mg | $118.00 $148.00 | 26 | |
Binds sterols and can disrupt lipid rafts, potentially influencing transmembrane protein function, including TMEM92. | ||||||
Capsazepine | 138977-28-3 | sc-201098 sc-201098A | 5 mg 25 mg | $148.00 $459.00 | 11 | |
A TRPV1 channel blocker that can inhibit some transmembrane channels, potentially influencing TMEM92. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Has known membrane-interacting properties which can affect transmembrane protein function. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Known as a tyrosine kinase inhibitor, it can potentially influence transmembrane receptor tyrosine kinases and thus, indirectly TMEM92. | ||||||
Lidocaine | 137-58-6 | sc-204056 sc-204056A | 50 mg 1 g | $51.00 $131.00 | ||
Local anesthetic that can affect membrane protein function, potentially influencing TMEM92. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
By altering membrane cholesterol levels, they might affect the functionality of certain transmembrane proteins. | ||||||