Date published: 2025-11-1

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THEGL Activators

The functional activity of THEGL, a protein encoded by a gene with limited characterization, could potentially be influenced by various compounds that affect metabolic pathways and enzyme functions. Fatty acids, such as palmitic acid, might serve as substrates or regulators for THEGL if it functions as a thioesterase, thereby potentially enhancing its enzymatic activity. Coenzyme A (CoA), essential for fatty acid metabolism, could also be involved in reactions catalyzed by thioesterases like THEGL, suggesting that supplementing with CoA might enhance THEGL's activity.

Compounds that modulate metabolic pathways, such as AICAR (an AMPK activator), Berberine, and Metformin, could indirectly influence THEGL's activity, particularly if THEGL is involved in energy metabolism or lipid metabolism. Resveratrol, known for its impact on metabolic pathways and gene expression, might also affect THEGL's function, especially if it plays a role in these processes. Curcumin, with its broad effects on cell signaling, and Pioglitazone, a PPAR-gamma agonist, might modulate THEGL's function if it is involved in metabolic processes, inflammation, or insulin signaling pathways. Omega-3 fatty acids, like EPA and DHA, known to influence lipid metabolism, might also affect the activity of enzymes like THEGL. NAD+ supplementation, enhancing mitochondrial function and energy metabolism, could potentially influence THEGL if it is involved in related metabolic processes. Spermidine, promoting autophagy and influencing cellular aging and differentiation, could support THEGL's function if it is involved in these cellular processes. Forskolin, by increasing cAMP levels, might affect enzymes involved in metabolic pathways, including THEGL, if it plays a role in cAMP-dependent signaling pathways.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Palmitic Acid

57-10-3sc-203175
sc-203175A
25 g
100 g
$112.00
$280.00
2
(0)

Fatty acids like palmitic acid can be substrates or regulators of thioesterase activity. Enhancing the availability of fatty acids could potentially influence THEGL's enzymatic activity if it functions as a thioesterase.

Coenzyme A

85-61-0 anhydroussc-211123
sc-211123A
sc-211123B
sc-211123C
10 mg
25 mg
100 mg
250 mg
$70.00
$116.00
$410.00
$785.00
1
(1)

Coenzyme A is essential for fatty acid metabolism and could be involved in reactions catalyzed by thioesterases like THEGL. Supplementing with CoA might enhance THEGL's enzymatic activity if it is involved in CoA-dependent processes.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$60.00
$270.00
$350.00
48
(2)

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is an AMPK activator that can influence metabolic pathways, including those involving thioesterases. It could indirectly affect THEGL's activity in energy metabolism.

Berberine

2086-83-1sc-507337
250 mg
$90.00
1
(0)

Berberine modulates metabolic processes and could influence the activity of enzymes involved in lipid metabolism, potentially affecting THEGL if it plays a role in these pathways.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol influences metabolic pathways and gene expression. If THEGL is involved in metabolic processes, Resveratrol might indirectly influence its activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin modulates various signaling pathways and could indirectly influence the function of THEGL, especially if it is involved in metabolic processes or inflammation-related pathways.

Metformin

657-24-9sc-507370
10 mg
$77.00
2
(0)

Metformin, an AMPK activator, is commonly used to regulate glucose and lipid metabolism. It could indirectly affect THEGL's function if THEGL is involved in similar metabolic pathways.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$54.00
$123.00
13
(1)

Pioglitazone, a PPAR-gamma agonist, influences lipid metabolism and insulin sensitivity. It could potentially affect THEGL's activity if THEGL is involved in pathways related to lipid metabolism or insulin signaling.

NAD+, Free Acid

53-84-9sc-208084B
sc-208084
sc-208084A
sc-208084C
sc-208084D
sc-208084E
sc-208084F
1 g
5 g
10 g
25 g
100 g
1 kg
5 kg
$56.00
$186.00
$296.00
$655.00
$2550.00
$3500.00
$10500.00
4
(2)

NAD+ supplementation can enhance mitochondrial function and energy metabolism. If THEGL is involved in mitochondrial processes or energy metabolism, NAD+ might indirectly influence its activity.

Spermidine

124-20-9sc-215900
sc-215900B
sc-215900A
1 g
25 g
5 g
$56.00
$595.00
$173.00
(2)

Spermidine promotes autophagy and might influence cellular aging and differentiation processes. If THEGL is involved in such processes, Spermidine could support its function.