Date published: 2026-1-8

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TH Antibodies

Santa Cruz Biotechnology features a diverse variety of TH Antibodies for the detection and analysis of tyrosine hydroxylase, a key enzyme in the biosynthesis of catecholamines. TH Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Tyrosine hydroxylase plays a critical role in the conversion of tyrosine to L-DOPA, the precursor to dopamine, norepinephrine, and epinephrine. The enzyme is essential for neurotransmitter synthesis and is implicated in numerous neurological disorders, making it a significant target for research in neurobiology and pharmacology. Understanding the regulation and function of tyrosine hydroxylase is crucial for developing therapeutic strategies for conditions such as Parkinson's disease and depression. Researchers worldwide rely on TH monoclonal antibodies to advance their understanding of neurotransmitter pathways and cellular signaling mechanisms. The high specificity of TH monoclonal antibodies enables precise detection and quantification of tyrosine hydroxylase in various experimental settings. Investigating tyrosine hydroxylase expression patterns helps reveal important insights about neurological development and disease progression. Santa Cruz Biotechnology monoclonal antibodies for TH detection continue to support breakthrough discoveries in neuroscience research and therapeutic development.

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TH Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Tyrosine Hydroxylase Antibody (F-11)

sc-25269mouse IgG2a κ1-196 (h)WB, IP, IF, IHC(P), ELISAm, r, h
202
(37)

Tyrosine Hydroxylase Antibody (TOH A1.1)

sc-47708mouse IgG1 κFL (r)WB, IP, IF, FCMm, r, h
5
(3)

Tyrosine Hydroxylase Antibody (A-1)

sc-374047mouse IgG1 κ500-526 (h)WB, IP, IF, ELISAm, r, h
10
(5)

Tyrosine Hydroxylase Antibody (A-6)

sc-374048mouse IgM κ500-526 (h)WB, IP, IF, ELISAm, r, h
7
(2)

Tyrosine Hydroxylase Antibody (6A477)

sc-73151mouse IgG1 κFL (r)WB, IP, IF, FCMm, r, h
1
(1)

TH CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Tyrosine Hydroxylase CRISPR/Cas9 KO Plasmid (h)

sc-400273hGene KnockoutGFP0
(0)

Tyrosine Hydroxylase CRISPR/Cas9 KO Plasmid (h2)

sc-400273-KO-2hGene KnockoutGFP0
(0)

Tyrosine Hydroxylase HDR Plasmid (h2)

sc-400273-HDR-2hHomology Directed RepairPuromycin0
(0)

Tyrosine Hydroxylase Double Nickase Plasmid (h)

sc-400273-NIChGene KnockoutPuromycin0
(0)

Tyrosine Hydroxylase Double Nickase Plasmid (h2)

sc-400273-NIC-2hGene KnockoutPuromycin0
(0)

Tyrosine Hydroxylase CRISPR/Cas9 KO Plasmid (m)

sc-423379mGene KnockoutGFP0
(0)

Tyrosine Hydroxylase HDR Plasmid (m)

sc-423379-HDRmHomology Directed RepairPuromycin0
(0)

Tyrosine Hydroxylase Double Nickase Plasmid (m)

sc-423379-NICmGene KnockoutPuromycin0
(0)

Tyrosine Hydroxylase Double Nickase Plasmid (m2)

sc-423379-NIC-2mGene KnockoutPuromycin0
(0)

TH CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Tyrosine Hydroxylase CRISPR Activation Plasmid (h)

sc-400273-ACThGene ActivationPuro, Blast, Hygro0
(0)

Tyrosine Hydroxylase CRISPR Activation Plasmid (h2)

sc-400273-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Tyrosine Hydroxylase Lentiviral Activation Particles (h)

sc-400273-LAChGene ActivationPuro, Blast, Hygro0
(0)

Tyrosine Hydroxylase Lentiviral Activation Particles (h2)

sc-400273-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Tyrosine Hydroxylase CRISPR Activation Plasmid (m)

sc-423379-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Tyrosine Hydroxylase CRISPR Activation Plasmid (m2)

sc-423379-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Tyrosine Hydroxylase Lentiviral Activation Particles (m)

sc-423379-LACmGene ActivationPuro, Blast, Hygro0
(0)

Tyrosine Hydroxylase Lentiviral Activation Particles (m2)

sc-423379-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

TH siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Tyrosine Hydroxylase siRNA (h)

sc-36662hGene SilencingN/A0
(0)

Tyrosine Hydroxylase shRNA Plasmid (h)

sc-36662-SHhGene SilencingPuromycin0
(0)

Tyrosine Hydroxylase shRNA (h) Lentiviral Particles

sc-36662-VhGene SilencingPuromycin0
(0)

Tyrosine Hydroxylase siRNA (m)

sc-36661mGene SilencingN/A0
(0)

Tyrosine Hydroxylase shRNA Plasmid (m)

sc-36661-SHmGene SilencingPuromycin0
(0)

Tyrosine Hydroxylase shRNA (m) Lentiviral Particles

sc-36661-VmGene SilencingPuromycin0
(0)

Tyrosine Hydroxylase siRNA (r)

sc-270461rGene SilencingN/A0
(0)

Tyrosine Hydroxylase shRNA Plasmid (r)

sc-270461-SHrGene SilencingPuromycin0
(0)

Tyrosine Hydroxylase shRNA (r) Lentiviral Particles

sc-270461-VrGene SilencingPuromycin0
(0)