Tyrosine Hydroxylase Antibody (TOH A1.1): sc-47708
- Tyrosine Hydroxylase Antibody (TOH A1.1) is a mouse monoclonal IgG1 κ, cited in 5 publications, provided at 200 µg/ml
- raised against tyrosine hydroxylase purified from pheochromocytoma cells of rat origin
- recommended for detection of TH of mouse, rat and human origin by WB, IP, IF and FCM
- See Tyrosine Hydroxylase (F-11): sc-25269 for Tyrosine Hydroxylase antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Tyrosine Hydroxylase Antibody (TOH A1.1). This work is in progress.
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SEE ALSO...
TH Antibody (TOH A1.1) is a mouse monoclonal IgG1 antibody that detects tyrosine hydroxylase (TH) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). TH is a critical enzyme that catalyzes the conversion of tyrosine to L-dopa, representing the rate-limiting step in the biosynthesis of catecholamines, including dopamine, adrenaline, and noradrenaline. The proper functioning of TH is essential for maintaining normal levels of these neurotransmitters, which are vital for various physiological processes, including mood regulation, stress response, and motor control. Dysregulation of TH activity has been implicated in the pathogenesis of neurological disorders, particularly Parkinson′s disease, where reduced dopamine levels lead to significant motor and cognitive impairments. Additionally, the regulation of the TH gene is complex, involving transcription factor binding sites such as the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), which respond to various signaling pathways. Anti-TH antibody (TOH A1.1) serves as an invaluable tool for researchers studying catecholamine biosynthesis and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tyrosine Hydroxylase Antibody (TOH A1.1) | sc-47708 | 200 µg/ml | $322.00 |