TFIIIC63 Activators
TFIIIC63 activators belong to a class of chemical compounds designed to modulate the activity of TFIIIC63, a subunit of the transcription factor TFIIIC (Transcription Factor for Polymerase III C). TFIIIC is a multi-subunit protein complex responsible for the transcription of RNA polymerase III (Pol III)-dependent genes, which encode essential cellular RNAs like transfer RNAs (tRNAs), 5S ribosomal RNA, and other small non-coding RNAs. These genes are involved in fundamental cellular processes such as protein synthesis and RNA maturation. TFIIIC63 plays a pivotal role in recruiting TFIIIC to the promoter regions of Pol III-transcribed genes, initiating their transcription.
TFIIIC63 activators are designed to interact with TFIIIC63 and potentially influence its binding to Pol III gene promoters, modulating the transcriptional activity of these genes. By targeting TFIIIC63, these compounds may impact the expression of Pol III-dependent genes, ultimately influencing crucial cellular processes. Research on TFIIIC63 activators provides insights into the complex regulation of gene expression and the role of transcription factors in controlling the synthesis of essential RNA molecules. Understanding the molecular interactions between TFIIIC63 and its activators is essential for deciphering the intricate processes that govern gene transcription by Pol III and its significance in cellular physiology. Further investigation is needed to elucidate the precise mechanisms of action and potential biological consequences associated with TFIIIC63 activation, contributing to our knowledge of transcriptional regulation and gene expression control.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid regulates gene transcription and may indirectly affect the expression of TFIIIC63 as part of broader gene regulation mechanisms. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C and can lead to changes in transcription factor activity, potentially impacting TFIIIC63 expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
This DNA methyltransferase inhibitor alters DNA methylation, potentially affecting the expression of a wide range of genes including transcription factors. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels and potentially enhancing transcription of various genes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG has been shown to influence gene expression patterns and could have an effect on TFIIIC63 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As an HDAC inhibitor, Trichostatin A alters chromatin structure and gene expression, possibly affecting TFIIIC63. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is an HDAC inhibitor that can change gene expression patterns, potentially influencing TFIIIC63 levels. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR signaling, which is involved in the regulation of protein synthesis and gene expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium affects several signaling pathways, including those involved in gene expression, and could influence TFIIIC63 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone acts as a glucocorticoid receptor agonist, influencing the transcription of many genes, possibly including TFIIIC63. | ||||||