Date published: 2026-4-1

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Tensin3 Inhibitors

The category of Tensin3 Inhibitors encompasses a broad spectrum of compounds that, rather than directly targeting Tensin3, aim to modulate the signaling pathways and cellular processes in which Tensin3 is involved. Given Tensin3's crucial role in integrating signals from the extracellular matrix to the actin cytoskeleton and its involvement in focal adhesion dynamics, the selected inhibitors focus on altering the cellular environment or signaling cascades that regulate Tensin3 expression or function. This approach leverages the interconnected nature of cellular signaling networks, targeting upstream or downstream factors that influence Tensin3 activity, including tyrosine kinases, PI3K, MAPKs, and integrins.

By focusing on compounds known to affect pathways critical for Tensin3's function, this strategy provides a means to explore the biological functions of Tensin3 and its role in essential cellular activities like migration, proliferation, and survival. The selection of these compounds not only facilitates a deeper understanding of Tensin3's involvement in cellular signaling but also exemplifies broader principles of drug action and the potential of targeted chemical intervention to modulate complex cellular functions. This methodology underscores the potential of pharmacological research to uncover novel strategies for diseases associated with aberrant Tensin3 activity, providing a foundation for further investigation into the mechanisms of action of Tensin3 and the development of new approaches to modulate its activity.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$94.00
$227.00
30
(1)

Src family kinase inhibitor, could disrupt signaling pathways involving Tensin3.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

PI3K inhibitor, might affect downstream signaling pathways associated with Tensin3.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$70.00
$145.00
51
(1)

Broad-spectrum tyrosine kinase inhibitor, potentially affecting Tensin3's role in focal adhesion.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

ROCK inhibitor, could influence cytoskeletal reorganization and Tensin3's cellular functions.

PF-562271

717907-75-0sc-478488
sc-478488A
sc-478488B
5 mg
10 mg
50 mg
$312.00
$474.00
$1124.00
3
(1)

FAK inhibitor, might impact integrin signaling pathways relevant to Tensin3.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, potentially modulating pathways that influence Tensin3 activity.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

p38 MAPK inhibitor, could affect stress response pathways associated with Tensin3.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

MEK inhibitor, might impact MAPK/ERK signaling pathways involving Tensin3.

ZSTK 474

475110-96-4sc-475495
5 mg
$75.00
(0)

PI3K inhibitor, could disrupt signaling cascades that modulate Tensin3 activity.

Cilengitide

188968-51-6sc-507335
5 mg
$215.00
(0)

Integrin inhibitor, might indirectly affect Tensin3 by altering cell-matrix interactions.