Tel1 Activators
Tel1 Activators is a class of chemicals that indirectly influence the Tel1 protein. These chemical compounds primarily exert their effects by modulating other proteins or processes that ultimately lead to the activation of Tel1, most notably the DNA damage response. This response is a critical cellular mechanism that detects and repairs damaged DNA, with Tel1 playing a central role.
Chemicals like Resveratrol and Curcumin activate SIRT1 and ATM respectively, proteins that are directly involved in the DNA damage response. Upon activation, these proteins can further activate Tel1. On the other hand, agents like Quercetin, EGCG, and Ellagic Acid induce the DNA damage response itself, thereby triggering Tel1 activation. Other chemicals, such as Sulforaphane, work a bit differently by activating Nrf2, a transcription factor that regulates the expression of genes involved in the DNA damage response, indirectly leading to Tel1 activation. In essence, these chemicals can stimulate Tel1 activity by acting upstream in cellular pathways related to DNA repair and cellular stress response.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a polyphenolic compound that can stimulate SIRT1, which in turn activates Tel1 through deacetylation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can activate ATM, a protein related to Tel1, promoting its association with DNA damage sites and indirectly activating Tel1. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid that can trigger DNA damage response, subsequently activating Tel1. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a catechin that can induce oxidative DNA damage, leading to Tel1 activation as a part of the DNA damage response. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Ellagic Acid can trigger DNA damage response and activate Tel1. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein can activate ATM, which subsequently activates Tel1. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine can induce DNA damage response, leading to Tel1 activation. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $146.00 $582.00 $6248.00 | 4 | |
Lycopene can induce oxidative DNA damage, leading to Tel1 activation. | ||||||
Gallotannin | 1401-55-4 | sc-202619 sc-202619A sc-202619B sc-202619C sc-202619D sc-202619E sc-202619F | 1 g 10 g 100 g 250 g 1 kg 2.5 kg 5 kg | $26.00 $37.00 $67.00 $78.00 $234.00 $536.00 $983.00 | 12 | |
Tannic Acid can induce DNA damage response, which leads to Tel1 activation. | ||||||
Chlorogenic Acid | 327-97-9 | sc-204683 sc-204683A | 500 mg 1 g | $47.00 $69.00 | 1 | |
Chlorogenic Acid can activate ATM, thereby indirectly activating Tel1. | ||||||