TDRD6 Inhibitors
Chemical inhibitors of TDRD6 play a crucial role in modulating the structure and function of the chromatoid body by targeting the microtubule networks essential for its maintenance. Paclitaxel, a stabilizer of microtubules, can inhibit TDRD6 by preventing microtubule disassembly, thus potentially affecting the dynamic processes required for TDRD6 to function properly within the chromatoid body. Similarly, colchicine and vinblastine, both known to bind tubulin and inhibit microtubule polymerization, can disrupt microtubule-dependent processes integral to TDRD6's role in the chromatoid body. Nocodazole, which hinders microtubule polymerization, can inhibit TDRD6 by compromising the structural integrity of the chromatoid body. Vincristine also targets tubulin to inhibit microtubule formation, which can, in turn, affect TDRD6 by disrupting the pathways crucial to the chromatoid body's function.
Further influencing the microtubule apparatus and consequently TDRD6 are chemicals like podophyllotoxin, which inhibits microtubule assembly, and eribulin, which disrupts microtubule growth without affecting the shortening phase. These interferences can inhibit TDRD6 by disturbing the microtubule dynamics that are essential for the chromatoid body's function. Additionally, compounds such as griseofulvin and thiabendazole, both capable of disrupting microtubule function, can alter the necessary microtubule-dependent processes for TDRD6's proper localization and function within the chromatoid body. Albendazole, mebendazole, and parbendazole, which respectively cause degenerative alterations in cytoplasmic microtubules, disrupt microtubule synthesis, and interfere with microtubule and spindle formation, can inhibit TDRD6 through similar mechanisms, thereby affecting the integrity and function of the chromatoid body where TDRD6 operates.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and prevents their disassembly, which can inhibit TDRD6 because TDRD6 is involved in the formation of the chromatoid body, a structure that relies on microtubule dynamics for its maintenance and function. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin, inhibiting microtubule polymerization, which can affect TDRD6 by disrupting microtubule-dependent processes that are essential for the proper function of the chromatoid body, where TDRD6 is localized. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule networks by inhibiting their polymerization, which can inhibit TDRD6 by affecting the structural integrity of the chromatoid body, which relies on microtubules for its proper organization and function. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine binds to tubulin, interfering with microtubule assembly, which can inhibit TDRD6 by preventing the correct assembly of the chromatoid body, a structure that depends on microtubules and is associated with TDRD6. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Podophyllotoxin inhibits microtubule assembly by binding to tubulin, which can inhibit TDRD6 by interfering with microtubule dynamics, essential for the proper functioning of the chromatoid body, where TDRD6 is localized. | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | $865.00 | ||
Eribulin inhibits the growth phase of microtubules without affecting the shortening phase, which can inhibit TDRD6 by disturbing microtubule dynamics that are essential for the function of the chromatoid body, a cellular structure associated with TDRD6. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin disrupts microtubule function by binding to tubulin, which can inhibit TDRD6 activity by altering the microtubule-dependent processes that are essential for the proper function of the chromatoid body, where TDRD6 is localized. | ||||||
Thiabendazole | 148-79-8 | sc-204913 sc-204913A sc-204913B sc-204913C sc-204913D | 10 g 100 g 250 g 500 g 1 kg | $31.00 $82.00 $179.00 $306.00 $561.00 | 5 | |
Thiabendazole inhibits microtubule polymerization, which can inhibit TDRD6 by affecting the microtubule structures that are necessary for the formation and function of the chromatoid body, where TDRD6 is involved. | ||||||
Albendazole | 54965-21-8 | sc-210771 | 100 mg | $209.00 | 1 | |
Albendazole causes degenerative alterations in the cytoplasmic microtubules of cells, which can inhibit TDRD6 by disrupting the microtubule-dependent processes within the chromatoid body, a structure associated with TDRD6's function. | ||||||
Mebendazole | 31431-39-7 | sc-204798 sc-204798A | 5 g 25 g | $45.00 $87.00 | 2 | |
Mebendazole disrupts microtubule synthesis by binding to beta-tubulin, which can inhibit TDRD6 by compromising the microtubule architecture required for the chromatoid body's integrity and function, where TDRD6 is located. | ||||||