SUCLG2 Activators
Succinate-CoA ligase GDP/ADP-forming subunit beta (SUCLG2) is a protein that in humans is encoded by the SUCLG2 gene. This protein is a component of the succinate-CoA ligase enzyme, also known as succinyl-CoA synthetase, which plays a crucial role in the citric acid cycle (also known as the Krebs cycle or TCA cycle), a central pathway in cellular metabolism.
The succinate-CoA ligase enzyme is composed of two subunits, an alpha subunit and a beta subunit. SUCLG2 is one of the two possible beta subunits and is specific for the formation of GDP from GTP.In the citric acid cycle, succinate-CoA ligase catalyzes the conversion of succinyl-CoA to succinate, while simultaneously forming either ATP from ADP or GDP from GTP, depending on the specific beta subunit present. This step is unique in that it represents a substrate-level phosphorylation, directly generating a molecule of ATP or GTP.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dimethyl malonate | 108-59-8 | sc-239778 sc-239778A | 250 ml 1 L | $50.00 $104.00 | 1 | |
A derivative of malonate, might have similar indirect effects on the citric acid cycle and SUCLG2 activity. | ||||||
Triacsin C Solution in DMSO | 76896-80-5 | sc-200574 sc-200574A | 100 µg 1 mg | $187.00 $843.00 | 14 | |
An inhibitor of mitochondrial complex II, could indirectly influence metabolic pathways involving SUCLG2. | ||||||
Bongkrekic acid | 11076-19-0 | sc-205606 | 100 µg | $400.00 | 10 | |
An inhibitor of the adenine nucleotide translocase in mitochondria, could indirectly impact SUCLG2 function. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
An ATP synthase inhibitor, potentially influencing overall mitochondrial function and indirectly SUCLG2. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $33.00 $43.00 $63.00 $110.00 $188.00 $738.00 $2091.00 | 2 | |
A key intermediate in the citric acid cycle, supplementation could indirectly influence SUCLG2 activity. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Involved in the mitochondrial electron transport chain, could indirectly affect SUCLG2 function. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
An inhibitor of complex III in the electron transport chain, could indirectly influence SUCLG2 activity. | ||||||