SUCLG2 Antibody (A-2): sc-390818
- SUCLG2 Antibody (A-2) is a mouse monoclonal IgG1 κ SUCLG2 antibody, cited in 5 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 256-287 within an internal region of SUCLG2 of human origin
- SUCLG2 Antibody (A-2) is recommended for detection of SUCLG2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-SUCLG2 Antibody (A-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SUCLG2 Antibody (A-2) for WB and IHC(P) applications. These reagents are now offered in bundles with SUCLG2 Antibody (A-2) (see ordering information below).
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SUCLG2 Antibody (A-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects SUCLG2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-SUCLG2 antibody (A-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SUCLG2, also known as G-BETA or succinyl-CoA synthetase beta-G chain, is a 432 amino acid protein that plays a crucial role in the tricarboxylic acid cycle, a key metabolic pathway for energy production. SUCLG2 is primarily located in the mitochondria, where SUCLG2 dimerizes with SUCLG1 to form a GTP-specific enzyme complex, essential for catalyzing the conversion of succinate and CoA into succinyl-CoA, GDP, and inorganic phosphate. SUCLG2 is vital for efficient energy metabolism, and SUCLG2 dysregulation can lead to metabolic disorders. The gene encoding SUCLG2 is located on human chromosome 3p14.1, highlighting SUCLG2′s evolutionary conservation across species.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SUCLG2 Antibody (A-2) References:
- Ocular albinism: evidence for a defect in an intracellular signal transduction system. | Schiaffino, MV., et al. 1999. Nat Genet. 23: 108-12. PMID: 10471510
- Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase. | Fraser, ME., et al. 2000. J Mol Biol. 299: 1325-39. PMID: 10873456
- Adenine and guanine nucleotide-specific succinyl-CoA synthetases in the clonal beta-cell mitochondria: implications in the beta-cell high-energy phosphate metabolism in relation to physiological insulin secretion. | Kowluru, A. 2001. Diabetologia. 44: 89-94. PMID: 11206416
- Expression of two succinyl-CoA synthetases with different nucleotide specificities in mammalian tissues. | Lambeth, DO., et al. 2004. J Biol Chem. 279: 36621-4. PMID: 15234968
- Genetic evidence for the expression of ATP- and GTP-specific succinyl-CoA synthetases in multicellular eucaryotes. | Johnson, JD., et al. 1998. J Biol Chem. 273: 27580-6. PMID: 9765291
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SUCLG2 Antibody (A-2) | sc-390818 | 200 µg/ml | $316.00 | |||
SUCLG2 Antibody (A-2): m-IgG Fc BP-HRP Bundle | sc-530274 | 200 µg Ab; 10 µg BP | $354.00 | |||
SUCLG2 Antibody (A-2): m-IgGκ BP-HRP Bundle | sc-523696 | 200 µg Ab, 40 µg BP | $354.00 | |||
SUCLG2 Antibody (A-2): m-IgG1 BP-HRP Bundle | sc-543969 | 200 µg Ab; 20 µg BP | $354.00 | |||
SUCLG2 Antibody (A-2) AC | sc-390818 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SUCLG2 Antibody (A-2) HRP | sc-390818 HRP | 200 µg/ml | $316.00 | |||
SUCLG2 Antibody (A-2) FITC | sc-390818 FITC | 200 µg/ml | $330.00 | |||
SUCLG2 Antibody (A-2) PE | sc-390818 PE | 200 µg/ml | $343.00 | |||
SUCLG2 Antibody (A-2) Alexa Fluor® 488 | sc-390818 AF488 | 200 µg/ml | $357.00 | |||
SUCLG2 Antibody (A-2) Alexa Fluor® 546 | sc-390818 AF546 | 200 µg/ml | $357.00 | |||
SUCLG2 Antibody (A-2) Alexa Fluor® 594 | sc-390818 AF594 | 200 µg/ml | $357.00 | |||
SUCLG2 Antibody (A-2) Alexa Fluor® 647 | sc-390818 AF647 | 200 µg/ml | $357.00 | |||
SUCLG2 Antibody (A-2) Alexa Fluor® 680 | sc-390818 AF680 | 200 µg/ml | $357.00 | |||
SUCLG2 Antibody (A-2) Alexa Fluor® 790 | sc-390818 AF790 | 200 µg/ml | $357.00 | |||
SUCLG2 (A-2) Neutralizing Peptide | sc-390818 P | 100 µg/0.5 ml | $68.00 |