Stat3 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colivelin | 867021-83-8 | sc-361153 | 1 mg | $612.00 | 32 | |
Colivelin is a distinctive compound recognized for its role as a Stat3 modulator. It engages in specific molecular interactions that influence signal transduction pathways, particularly those related to cellular growth and differentiation. Its unique structural features facilitate selective binding to Stat3, promoting dimerization and subsequent transcriptional activity. This compound's reactivity profile allows it to effectively alter downstream gene expression, showcasing its potential in regulating cellular responses. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates Stat3 by inhibiting negative regulators. Its presence in grapes and red wine makes it a natural compound of interest in cancer and immune response research. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin suppresses Stat3 activation by interfering with its phosphorylation. With anti-inflammatory and antioxidant properties, it holds promise in inflammation and cancer studies. Derived from turmeric, it's a potential Stat3-related therapeutic compound. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG inhibits Stat3 phosphorylation and nuclear translocation. Found in green tea, its antioxidant properties contribute to its relevance in cancer and inflammation studies. | ||||||
Stat3 inhibitor V, stattic | 19983-44-9 | sc-202818 sc-202818A sc-202818B sc-202818C sc-202818D sc-202818E sc-202818F | 25 mg 100 mg 250 mg 500 mg 1 g 2.5 g 5 g | $130.00 $196.00 $274.00 $512.00 $731.00 $1408.00 $2091.00 | 114 | |
Stattic selectively inhibits Stat3 activation, showing promise in targeting Stat3-related pathways in diseases like cancer. | ||||||
Stat3 Inhibitor VI, S3I-201 | 501919-59-1 | sc-204304 | 10 mg | $151.00 | 104 | |
S3I-201 inhibits Stat3 dimerization and DNA binding, making it a valuable tool in Stat3-related research. | ||||||
Ruxolitinib Phosphate | 1092939-17-7 | sc-396768 sc-396768A sc-396768B sc-396768C | 5 mg 10 mg 50 mg 100 mg | $116.00 $181.00 $310.00 $486.00 | 1 | |
Ruxolitinib Phosphate is a selective inhibitor of the Janus kinase (JAK) pathway, particularly targeting JAK1 and JAK2, which play crucial roles in the activation of Stat3. By disrupting the phosphorylation of Stat3, it modulates downstream signaling cascades that govern various cellular processes. Its unique binding affinity alters the conformational dynamics of Stat3, impacting its ability to dimerize and translocate to the nucleus, thereby influencing gene transcription and cellular behavior. | ||||||
Cucurbitacin I | 2222-07-3 | sc-203010 | 1 mg | $250.00 | 9 | |
Cucurbitacin I inhibits Stat3 phosphorylation and activation, holding potential in cancer and inflammation studies. | ||||||
Cryptotanshinone | 35825-57-1 | sc-280649 | 10 mg | $119.00 | 1 | |
Cryptotanshinone suppresses Stat3 activation and nuclear translocation, showing promise in cancer and inflammation research. | ||||||
Tyrphostin AG 879 | 148741-30-4 | sc-3557 sc-3557A | 5 mg 25 mg | $83.00 $328.00 | 4 | |
AG-879 inhibits Stat3 tyrosine kinase activity, making it relevant in Stat3-related therapeutic development and cancer research. | ||||||