STAMBPL1 inhibitors are a class of chemical compounds that have garnered significant interest in the field of molecular biology and cellular signaling research. STAMBPL1, short for STAM-binding protein-like 1 is a protein that plays a crucial role in cellular processes related to protein trafficking, endocytosis, and ubiquitination. The term STAMBPL1 inhibitors refers to a group of molecules designed to selectively target and disrupt the activity of the STAMBPL1 protein. These inhibitors are primarily used as valuable tools in laboratory settings to investigate the intricate mechanisms governing intracellular trafficking and ubiquitin-mediated processes.
STAMBPL1 inhibitors typically function by binding to the STAMBPL1 protein and interfering with its role in cellular processes. By doing so, they can affect the sorting and degradation of specific proteins, impacting various cellular pathways. Researchers employ STAMBPL1 inhibitors to better understand the consequences of altered STAMBPL1 activity, helping to unravel the complex web of protein regulation and cellular trafficking. This research can provide insights into the fundamental cellular mechanisms that underlie processes such as endocytosis and protein turnover, shedding light on the broader field of cell biology and potentially uncovering novel avenues for future research and discovery.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide inhibits eukaryotic protein synthesis, which could lead to a reduction in the overall expression of proteins including STAMBPL1. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase action and potentially decreasing the transcription of genes such as STAMBPL1. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide is known to inhibit transcriptional activity, which could extend to the downregulation of STAMBPL1 gene expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG132 is a proteasome inhibitor that can alter protein turnover, potentially reducing expression levels of proteins including STAMBPL1. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine affects lysosomal acidity and function, which can have downstream effects on cellular processes and potentially decrease STAMBPL1 expression. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib is a proteasome inhibitor that may indirectly reduce STAMBPL1 levels by disrupting proteostasis and protein turnover pathways. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1 is a BET bromodomain inhibitor that may affect the transcription of many genes, potentially including STAMBPL1, by altering chromatin accessibility. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $166.00 $322.00 | 436 | |
Puromycin causes premature chain termination during protein synthesis, which could nonspecifically lead to decreased STAMBPL1 protein levels. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
SAHA is an HDAC inhibitor that can change gene expression profiles, possibly affecting STAMBPL1 expression by altering chromatin structure. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is an HDAC inhibitor that can lead to hyperacetylation of histones, affecting gene expression patterns which may include STAMBPL1. | ||||||