STAF42 Activators
TSTAF42 Activators comprises a group of compounds that can influence the activity of the STAF42 protein by targeting specific cellular pathways and processes. These activators include phorbol 12-myristate 13-acetate (PMA), forskolin, ionomycin, trichostatin A (TSA), valproic acid, 5-azacytidine, and decitabine. Each of these chemicals operates through distinct mechanisms, primarily centered around cellular signaling and epigenetic regulation.
PMA acts as an activator of Protein Kinase C (PKC), triggering phosphorylation events in various cellular pathways. STAF42 interacts with PKC-mediated pathways, PMA can indirectly modulate its activity. Forskolin elevates intracellular cAMP levels and activates Protein Kinase A (PKA), which can lead to phosphorylation events affecting cellular processes that STAF42 may be involved in. Ionomycin, a calcium ionophore, increases intracellular calcium levels, influencing calcium-dependent signaling pathways connected to STAF42. Trichostatin A (TSA) and valproic acid, by inhibiting HDACs, these compounds increase histone acetylation, impacting STAF42 plays a role in epigenetic regulation or chromatin remodeling. Additionally, 5-azacytidine and decitabine are inhibitors of DNA methyltransferases (DNMTs), reducing DNA methylation patterns.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a Protein Kinase C (PKC) activator, potentially modulating STAF42 by influencing PKC-dependent signaling pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin elevates cAMP levels and activates Protein Kinase A (PKA), potentially impacting STAF42 if it interacts with the PKA pathway. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin is a calcium ionophore, increasing intracellular calcium levels, which may influence calcium-dependent signaling pathways connected to STAF42, if such interactions exist. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
TSA is an inhibitor of Histone Deacetylases (HDACs), potentially affecting STAF42 by increasing histone acetylation and influencing chromatin regulation. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid is another HDAC inhibitor, similar to TSA, potentially impacting STAF42 by enhancing histone acetylation and influencing chromatin regulation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is an inhibitor of DNA methyltransferases (DNMTs), reducing DNA methylation patterns and potentially affecting STAF42 if it is involved in e1o 5-azacytidine, potentially impacting STAF42 by modulating DNA methylation and gene expression patterns. | ||||||