STAF42 Antibody (B-11): sc-398787
- STAF42 Antibody (B-11) is a mouse monoclonal IgG2a κ STAF42 antibody provided at 200 µg/ml
- raised against amino acids 136-248 mapping within an internal region of STAF42 of human origin
- STAF42 Antibody (B-11) is recommended for detection of STAF42 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-STAF42 Antibody (B-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of STAF42 (B-11): sc-398787.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for STAF42 Antibody (B-11) for WB applications. These reagents are now offered in bundles with STAF42 Antibody (B-11) (see ordering information below).
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STAF42 Antibody (B-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects STAF42 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). STAF42 (B-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. STAF42, also known as SPT3-associated factor 42, transcriptional adapter 1, ADA1, HFI1, or hADA1, is a 335 amino acid nuclear protein that plays a crucial role in transcriptional regulation as a component of the STAGA transcription coactivator-histone acetyltransferase complex. This complex is essential for the regulation of gene expression, influencing various cellular processes such as differentiation, proliferation, and response to environmental signals. STAF42 is encoded on human chromosome 1, which harbors numerous disease-associated genes, including those linked to familial adenomatous polyposis, Stickler syndrome, Parkinson′s disease, Gaucher disease, schizophrenia, and Usher syndrome. Chromosome 1 is also implicated in various cancers, including head and neck cancer, malignant melanoma, and multiple myeloma, making STAF42 and its interactions vital for understanding these diseases and developing potential therapeutic strategies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
STAF42 Antibody (B-11) References:
- Gaucher disease and parkinsonism: a phenotypic and genotypic characterization. | Tayebi, N., et al. 2001. Mol Genet Metab. 73: 313-21. PMID: 11509013
- Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. | Martinez, E., et al. 2001. Mol Cell Biol. 21: 6782-95. PMID: 11564863
- Exclusion of an extracolonic disease modifier locus on chromosome 1p33-36 in a large Swiss familial adenomatous polyposis kindred. | Plasilova, M., et al. 2004. Eur J Hum Genet. 12: 365-71. PMID: 14735163
- Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damage. | Gamper, AM. and Roeder, RG. 2008. Mol Cell Biol. 28: 2517-27. PMID: 18250150
- Fas-associated factor 1 and Parkinson's disease. | Betarbet, R., et al. 2008. Neurobiol Dis. 31: 309-15. PMID: 18573343
- Strong evidence for a novel schizophrenia risk locus on chromosome 1p31.1 in homogeneous pedigrees from Tamil Nadu, India. | Holliday, EG., et al. 2009. Am J Psychiatry. 166: 206-15. PMID: 18829870
- Analysis of the vitreous membrane in a case of type 1 Stickler syndrome. | Yokoi, T., et al. 2009. Graefes Arch Clin Exp Ophthalmol. 247: 715-8. PMID: 19089441
- Gain of chromosome arm 1q in patients in relapse and progression of multiple myeloma. | Balcárková, J., et al. 2009. Cancer Genet Cytogenet. 192: 68-72. PMID: 19596256
- Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41. | Eudy, JD., et al. 1998. Genomics. 50: 382-4. PMID: 9676434
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
STAF42 Antibody (B-11) | sc-398787 | 200 µg/ml | $316.00 | |||
STAF42 Antibody (B-11): m-IgG Fc BP-HRP Bundle | sc-530928 | 200 µg Ab; 10 µg BP | $354.00 | |||
STAF42 Antibody (B-11): m-IgGκ BP-HRP Bundle | sc-524485 | 200 µg Ab, 40 µg BP | $354.00 | |||
STAF42 Antibody (B-11): m-IgG2a BP-HRP Bundle | sc-547635 | 200 µg Ab; 10 µg BP | $354.00 | |||
STAF42 Antibody (B-11) AC | sc-398787 AC | 500 µg/ml, 25% agarose | $416.00 | |||
STAF42 Antibody (B-11) HRP | sc-398787 HRP | 200 µg/ml | $316.00 | |||
STAF42 Antibody (B-11) FITC | sc-398787 FITC | 200 µg/ml | $330.00 | |||
STAF42 Antibody (B-11) PE | sc-398787 PE | 200 µg/ml | $343.00 | |||
STAF42 Antibody (B-11) Alexa Fluor® 488 | sc-398787 AF488 | 200 µg/ml | $357.00 | |||
STAF42 Antibody (B-11) Alexa Fluor® 546 | sc-398787 AF546 | 200 µg/ml | $357.00 | |||
STAF42 Antibody (B-11) Alexa Fluor® 594 | sc-398787 AF594 | 200 µg/ml | $357.00 | |||
STAF42 Antibody (B-11) Alexa Fluor® 647 | sc-398787 AF647 | 200 µg/ml | $357.00 | |||
STAF42 Antibody (B-11) Alexa Fluor® 680 | sc-398787 AF680 | 200 µg/ml | $357.00 | |||
STAF42 Antibody (B-11) Alexa Fluor® 790 | sc-398787 AF790 | 200 µg/ml | $357.00 |