Date published: 2026-4-1

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STAC2 Activators

Epigallocatechin gallate (EGCG) is renowned for its antioxidant properties and has the potential to influence various cellular signaling pathways, which could inadvertently modulate the activity of proteins such as STAC2. By mitigating oxidative stress and modulating kinase activity, EGCG could create a cellular environment conducive to STAC2 activation. Resveratrol, a polyphenolic compound, is known for activating sirtuins and AMP-activated protein kinase (AMPK). These proteins are involved in cellular stress responses and energy metabolism, which could intersect with the regulatory mechanisms of STAC2, possibly resulting in its activation. Curcumin, has a broad impact on cellular signaling, including the inhibition of certain kinases and the modulation of transcription factors. These widespread effects could lead to changes in the cellular landscape that promote the activation of STAC2.

Spermidine has been linked to the induction of autophagy via mTOR inhibition. Autophagy is a cellular housekeeping process that can influence the activity of a variety of proteins, potentially including STAC2, through the selective degradation of cellular components. 1,1-Dimethylbiguanide, Hydrochloride activates AMPK, a key regulator of cellular energy homeostasis. This can lead to a cascade of molecular events that might affect STAC2 function by shifting the metabolic state of the cell. Phosphatidic acid, a precursor for the synthesis of other lipids, plays a role in the activation of mTOR, a central regulator of cell growth and metabolism. Through mTOR signaling, phosphatidic acid could indirectly impact the activity of STAC2. Forskolin stimulates adenylyl cyclase, increasing intracellular cAMP levels, which can enhance the activity of proteins involved in cAMP-dependent pathways, potentially including STAC2. Sodium butyrate, a short-chain fatty acid, acts as a histone deacetylase inhibitor, modulating gene expression. This can lead to changes in cellular functions and protein interactions that may promote STAC2 activation.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A potent antioxidant that can influence various signaling cascades, potentially affecting the function of proteins like STAC2.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A polyphenolic compound known to activate sirtuins and AMPK, which can impact signaling pathways that may intersect with STAC2 activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Can modulate multiple signaling pathways, possibly leading to the activation of STAC2.

Spermidine

124-20-9sc-215900
sc-215900B
sc-215900A
1 g
25 g
5 g
$57.00
$607.00
$176.00
(2)

A polyamine known to induce autophagy through mTOR inhibition, a process that can alter cellular signaling and potentially enhance STAC2 function.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

An AMPK activator that can shift cellular metabolism and signaling, possibly affecting STAC2 activity.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

A histone deacetylase inhibitor that can alter gene expression and modulate protein function, potentially affecting STAC2.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

A flavonoid that can modulate various signaling pathways, potentially resulting in the activation of STAC2.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

An inhibitor of GSK-3β, which can modulate Wnt signaling, possibly impacting the signaling processes involving STAC2.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

An AMPK agonist that can mimic cellular energy depletion, thereby potentially influencing signaling pathways and STAC2 activity.