Ssa2 Activators
The category of Ssa2 Activators encompasses a range of chemical compounds that, while not directly activating Ssa2, influence its activity through modulation of stress response pathways and protein homeostasis. Ssa2, as a heat shock protein, is crucial in responding to cellular stress and aiding in protein folding. The first group of these compounds includes molecules that induce cellular stress or affect protein homeostasis, such as 17-AAG, Quercetin, Curcumin, Resveratrol, N-Acetylcysteine, and EGCG. These substances, by inducing stress responses or modulating signaling pathways, can indirectly lead to the upregulation of Ssa2. For example, HSP90 inhibitors like 17-AAG can increase the cellular need for chaperone activity, leading to an increased expression of Hsp70 family proteins, including Ssa2.
Another significant group comprises compounds and conditions that directly induce a stress response in cells, including Salicylic Acid, Caffeine, Sodium Arsenite, MG132, and oxidative agents like Hydrogen Peroxide. These substances can trigger cellular mechanisms that lead to the enhanced expression of stress response proteins such as Ssa2. For instance, oxidative stress inducers like Hydrogen Peroxide can trigger the upregulation of heat shock proteins as part of the cellular defense mechanism against stress.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
HSP90 inhibitor, potentially increasing cellular stress and upregulating HSP70 proteins like Ssa2. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Influences multiple cellular pathways including stress responses, potentially modulating Ssa2 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Affects gene expression and stress response pathways, potentially influencing Ssa2. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
An antioxidant that can modulate cellular stress responses, potentially affecting Ssa2 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A green tea polyphenol, may influence stress response pathways involving Ssa2. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $47.00 $94.00 $119.00 | 3 | |
Can induce heat shock response, potentially influencing Ssa2 expression. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Modulates various cellular processes, including stress responses, potentially affecting Ssa2. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $108.00 $780.00 | 3 | |
Induces cellular stress response, potentially upregulating Ssa2 expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor, can induce stress response, potentially enhancing Ssa2 activity. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Induces oxidative stress, potentially influencing Ssa2 expression. | ||||||