Date published: 2026-3-9

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SOAT Inhibitors

Santa Cruz Biotechnology now offers a broad range of SOAT inhibitors for use in various applications. SOAT inhibitors, also known as sterol O-acyltransferase inhibitors, are compounds that block the activity of the enzyme SOAT, which is involved in the esterification of cholesterol within cells. This inhibition is crucial in research focused on lipid metabolism, where understanding cholesterol homeostasis is key. By impeding the SOAT enzyme, these inhibitors allow scientists to explore how cholesterol esters are formed and stored, shedding light on the mechanisms underlying lipid storage and transport. SOAT inhibitors are particularly valuable in studying the biochemical pathways that govern cellular lipid droplets and their regulation, providing insights into broader aspects of cell biology, such as membrane dynamics and signal transduction. Researchers also employ these inhibitors to investigate the role of cholesterol esters in cellular processes and their implications in various physiological and environmental conditions. The availability of diverse SOAT inhibitors enables detailed analysis and experimentation, fostering advancements in biochemical research and expanding our understanding of lipid-related disorders. View detailed information on our available SOAT inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

CI 976

114289-47-3sc-203892B
sc-203892
sc-203892A
5 mg
10 mg
50 mg
$109.00
$189.00
$774.00
4
(1)

CI 976 functions as a SOAT by engaging in selective acylation reactions, showcasing its reactivity with nucleophiles through its electrophilic carbonyl group. This compound exhibits unique steric hindrance, which influences its interaction with various substrates, leading to distinct reaction pathways. The kinetics of its acylation processes are characterized by a rapid formation of intermediates, allowing for efficient modulation of target interactions and subsequent downstream effects.

TMP-153

128831-46-9sc-200649
sc-200649A
20 mg
100 mg
$119.00
$400.00
1
(1)

TMP-153 acts as a SOAT by facilitating acylation through its highly reactive carbonyl moiety, which is particularly susceptible to nucleophilic attack. Its unique structural features, including specific substituents, enhance its electrophilicity and direct the course of reaction pathways. The compound demonstrates notable selectivity in substrate interactions, resulting in distinct kinetic profiles that favor the formation of stable acylated products, thereby influencing downstream chemical transformations.

YM 750

138046-43-2sc-358844
sc-358844A
10 mg
50 mg
$138.00
$587.00
(0)

YM 750 functions as a SOAT by exhibiting a pronounced reactivity due to its electrophilic carbonyl group, which readily engages in nucleophilic acyl substitution. Its unique steric and electronic properties promote selective interactions with various nucleophiles, leading to distinct reaction kinetics. The compound's ability to stabilize transition states enhances its efficiency in acylation processes, ultimately shaping the outcome of subsequent chemical reactions and product formation.

GERI-BP002-A

119-47-1sc-221667
sc-221667A
100 mg
1 g
$43.00
$102.00
(0)

GERI-BP002-A acts as a SOAT through its highly reactive acyl chloride functionality, which facilitates rapid nucleophilic attack. The compound's unique electronic configuration allows for selective binding with a range of nucleophiles, influencing the reaction pathways. Its distinctive steric hindrance can modulate the rate of acylation, while the formation of stable intermediates plays a crucial role in determining the overall reaction dynamics and product specificity.

Sandoz 58-035

78934-83-5sc-215839
sc-215839A
5 mg
25 mg
$202.00
$836.00
11
(1)

Sandoz 58-035 exhibits remarkable reactivity as an acid halide, characterized by its ability to form transient acyl-enzyme complexes. This compound's electrophilic nature promotes swift interactions with nucleophiles, leading to diverse acylation patterns. Its unique steric environment influences the selectivity of reactions, while the presence of electron-withdrawing groups enhances its reactivity. Additionally, the compound's solubility properties facilitate its integration into various reaction media, impacting kinetics and product formation.

VULM 1457

228544-65-8sc-204390
sc-204390A
10 mg
50 mg
$185.00
$772.00
(0)

VULM 1457 stands out as a highly reactive acid halide, showcasing a propensity for rapid acyl transfer reactions. Its distinctive electronic configuration allows for enhanced electrophilicity, facilitating interactions with a range of nucleophiles. The compound's unique steric hindrance influences regioselectivity, while its ability to stabilize transition states accelerates reaction kinetics. Furthermore, VULM 1457's solvation characteristics play a crucial role in modulating reaction pathways and product distribution.